Avadol suspension 250 mg5ml (Strawberry)

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

Paracetamol

Boleh didapati daripada:

AV MANUFACTURING SDN.BHD

INN (Nama Antarabangsa):

Paracetamol

Unit dalam pakej:

90ml x 30 BOTTLE; 90ml x 1 BOTTLE; 60ml x 30 BOTTLE

Dikeluarkan oleh:

AV MANUFACTURING SDN.BHD

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP_
_) _
_ _
AVADOL
® SUSPENSION 250MG/5ML (ORANGE)
AVADOL
® SUSPENSION 250MG/5ML (STRAWBERRY)
Paracetamol (250 mg/5ml)
1
WHAT IS IN THIS LEAFLET
1.
What Avadol suspension is used for
2.
How Avadol suspension works
3.
Before you take Avadol suspension
4.
How to use Avadol suspension
5.
While you are using Avadol
suspension
6.
Side effects
7.
Storage and Disposal
8.
Product Description
9.
Manufacturer & Product
Registration Holder
10.
Date of revision
1.
WHAT AVADOL SUSPENSION IS USED FOR
Avadol suspension is used for the relief
of fever, headache, and symptoms of
cold and flu, toothache, discomfort of
teething and fever after vaccination.
2.
HOW AVADOL SUSPENSION WORKS
Avadol suspension contains the active
ingredient paracetamol which is a
painkiller and also reduces your
temperature when you have a fever. It is
absorbed fast by the body which means
it can take action in a short time.
3.
BEFORE YOU USE AVADOL SUSPENSION
- _When you must not use it _

If you have ever had allergic
reaction to paracetamol or any of the
other ingredients in this product.

If you are taking any other
medicines containing paracetamol.

If you had severe and active liver
problem.
_-Before you start to use it _
Check with your doctor

If you suffer from liver or kidney
problems, including alcoholic liver
disease.

If you suffer from mild arthritis and
need to take painkillers every day.
_-Taking other medicines _
Please talk to your doctor or pharmacist,
if you are taking any of the medicines
below:

blood thinning medicines
(anticoagulants e.g. warfarin)

pain relievers on a daily basis

recently taken any other medicines,
including medicines
obtained without prescription.
_-Pregnancy and breast-feeding _
Use in pregnancy:

Considered to be the painkiller
of choice in pregnant patients.

Although it crosses placenta,
paracetamol is considered to be safe
in normal therapeutic doses for short-
term use in minor pain or fever in
pregnancy.
Use in breastfeeding:
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Ciri produk

_L
130.0MM
AVA
d
O
I
®
_SUSPENSION 250MG/5ML (STRAWBERRY)_
_SUSPENSION 250MG/5ML (ORANGE) _
NAME AND STRENGTH OF ACTIVE SUBSTANCE
Paracetamol 250mg/5ml
It also contains preservative Methylparaben 0.1
% w/v
PRODUCT DESCRIPTION:
AVADOL
'"
SUSPENSION STRAWBERRY:
A pink rose coloured and
strawberry flavour suspension.
AVADOL
'"
SUSPENSION ORANGE:
Orange coloured and orange
flavour suspension
PHARMACODYNAMICS
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with minimal anti-inflammatory properties.
_Analgesic _
The mechanism of analgesic action has not been fully
determined. Paracetamol may act predominantly by
inhibiting prostaglandin synthesis in the central nervous
system (specifically cyclooxygenase (COX)-2) and, to a
lesser extent, through a peripheral action by blocking
pain-impulse generation.
The peripheral action may also be due to inhibition of
prostaglandin synthesis or to inhibition of the synthesis or
actions of other substances that sensitize pain receptors to
mechanical or chemical stimulation.
_Antiovretic _
Paracetamol act centrally on the hypothalamic heat
regulating center to produce peripheral vasodilatation
resulting in increased blood flow through the shin, sweating
and heat loss
.. Earacetamol reduces fever by inhibiting the.
-
formulation and release of prostaglandins in the CNS and by
inhibiting endogenous pyrogens at the hypothalamic
thermoregulatory center.
PHARMACOKINETICS
Following oral administration paracetamol is rapidly
absorbed. Paracetamol absorption takes place mainly in the
small intestine and therefore the rate of absorption is
depending on the rate of gastric emptying. It has been
shown that drugs which delay gastric emptying also delay
the absorption of paracetamol whereas metoclopramide (a
drug which increases the rate of gastric emptying)
accelerates absorption of the analgesic through the total
amount absorbed doses not increase.
The presence of food in the stomach has also been reported
to reduce the rate of absorption of paracetamol. Alterati