Country: Malaysia
Bahasa: Inggeris
Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Paracetamol
AV MANUFACTURING SDN.BHD
Paracetamol
90 ml x 1 BOTTLE; 90 ml x 30 BOTTLE; 60ml x 30 BOTTLE
AV MANUFACTURING SDN.BHD
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP_ _) _ _ _ AVADOL ® SUSPENSION 250MG/5ML (ORANGE) AVADOL ® SUSPENSION 250MG/5ML (STRAWBERRY) Paracetamol (250 mg/5ml) 1 WHAT IS IN THIS LEAFLET 1. What Avadol suspension is used for 2. How Avadol suspension works 3. Before you take Avadol suspension 4. How to use Avadol suspension 5. While you are using Avadol suspension 6. Side effects 7. Storage and Disposal 8. Product Description 9. Manufacturer & Product Registration Holder 10. Date of revision 1. WHAT AVADOL SUSPENSION IS USED FOR Avadol suspension is used for the relief of fever, headache, and symptoms of cold and flu, toothache, discomfort of teething and fever after vaccination. 2. HOW AVADOL SUSPENSION WORKS Avadol suspension contains the active ingredient paracetamol which is a painkiller and also reduces your temperature when you have a fever. It is absorbed fast by the body which means it can take action in a short time. 3. BEFORE YOU USE AVADOL SUSPENSION - _When you must not use it _ If you have ever had allergic reaction to paracetamol or any of the other ingredients in this product. If you are taking any other medicines containing paracetamol. If you had severe and active liver problem. _-Before you start to use it _ Check with your doctor If you suffer from liver or kidney problems, including alcoholic liver disease. If you suffer from mild arthritis and need to take painkillers every day. _-Taking other medicines _ Please talk to your doctor or pharmacist, if you are taking any of the medicines below: blood thinning medicines (anticoagulants e.g. warfarin) pain relievers on a daily basis recently taken any other medicines, including medicines obtained without prescription. _-Pregnancy and breast-feeding _ Use in pregnancy: Considered to be the painkiller of choice in pregnant patients. Although it crosses placenta, paracetamol is considered to be safe in normal therapeutic doses for short- term use in minor pain or fever in pregnancy. Use in breastfeeding: Baca dokumen lengkap
_L 130.0MM AVA d O I ® _SUSPENSION 250MG/5ML (STRAWBERRY)_ _SUSPENSION 250MG/5ML (ORANGE) _ NAME AND STRENGTH OF ACTIVE SUBSTANCE Paracetamol 250mg/5ml It also contains preservative Methylparaben 0.1 % w/v PRODUCT DESCRIPTION: AVADOL '" SUSPENSION STRAWBERRY: A pink rose coloured and strawberry flavour suspension. AVADOL '" SUSPENSION ORANGE: Orange coloured and orange flavour suspension PHARMACODYNAMICS earace_talllil_l is_!! Cifil trally aG:!i_ng_fillalg_esic;__a nd_!!_ntigyre� with minimal anti-inflammatory properties. _Analgesic _ The mechanism of analgesic action has not been fully determined. Paracetamol may act predominantly by inhibiting prostaglandin synthesis in the central nervous system (specifically cyclooxygenase (COX)-2) and, to a lesser extent, through a peripheral action by blocking pain-impulse generation. The peripheral action may also be due to inhibition of prostaglandin synthesis or to inhibition of the synthesis or actions of other substances that sensitize pain receptors to mechanical or chemical stimulation. _Antiovretic _ Paracetamol act centrally on the hypothalamic heat regulating center to produce peripheral vasodilatation resulting in increased blood flow through the shin, sweating and heat loss .. Earacetamol reduces fever by inhibiting the. - formulation and release of prostaglandins in the CNS and by inhibiting endogenous pyrogens at the hypothalamic thermoregulatory center. PHARMACOKINETICS Following oral administration paracetamol is rapidly absorbed. Paracetamol absorption takes place mainly in the small intestine and therefore the rate of absorption is depending on the rate of gastric emptying. It has been shown that drugs which delay gastric emptying also delay the absorption of paracetamol whereas metoclopramide (a drug which increases the rate of gastric emptying) accelerates absorption of the analgesic through the total amount absorbed doses not increase. The presence of food in the stomach has also been reported to reduce the rate of absorption of paracetamol. Alterati Baca dokumen lengkap