APO-PROPRANOLOL 40MG

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

PROPRANOLOL HYDROCHLORIDE

Boleh didapati daripada:

PHARMAFORTE (MALAYSIA) SDN. BHD.

INN (Nama Antarabangsa):

PROPRANOLOL HYDROCHLORIDE

Unit dalam pakej:

100Tablet Tablets; 1000Tablet Tablets; 1000 Tablet Tablets

Dikeluarkan oleh:

APOTEX INC

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
_ _
APO-PROPRANOLOL
_ _
Propranolol (10mg, 40mg)
1
WHAT IS IN THIS LEAFLET
1. What Apo-Propranolol is used for
2. How Apo-Propranolol works
3. Before you use Apo-Propranolol
4. How to use Apo-Propranolol
5. While you are using it
6. Side effects
7.
Storage
and
Disposal
of
Apo-
Propranolol
8. Product Description
9.
Manufacturer
and
Product
Registration Holder
10. Date of revision
WHAT APO-PROPRANOLOL IS USED FOR
Apo-Propranolol can be used for:

high blood pressure

symptoms of chest pain (angina)

problems
affecting
the
beat
of
your
heart
(arrhythmias,
tachycardia)
It can also be used for:

severe headaches (migraine)

high blood pressure caused by a
tumour
on
the
adrenal
gland.
This
is
called
'phaeochromocytoma'
HOW APO-PROPRANOLOL WORKS
Propranolol
belongs
to
a
class
of
drugs
called
beta-blockers.
Propranolol
acts
by
blocking
the
action
of
certain
chemicals
(hormones) on the heart and the blood
vessels
and
affects,
amongst
other
things, the heart rate and the heart’s
workload.
BEFORE YOU USE APO-PROPRANOLOL - _When you must not use it _
Do not use this product if you have
bronchospasm and heart problem like
slow
heart
beat
(bradycardia)
and
heart block. Do not use this product
if you are allergic to_ _propranolol._ _
_Pregnancy and lactation _
Do not take Apo-Propranolol if you
are pregnant, trying to get pregnant or
think you may be pregnant.
Do not take Apo-Propranolol if you
are breast-feeding. Ask your doctor or
pharmacist for advice before taking
any medicine.
-
_Before you start to use it _
Before
you
start
to
use
this
medication,
you
should
let
your
doctor know if you have any other
medical
condition,
of
particular
importance
is
any
form
of
heart
disease._ _
-
_Taking other medicines _
Some
medications
might
cause
complications
when
taken
together
with
Apo-Propranolol.
These
medications
include
antiarrhythmic,
cardiac-depressant
drugs,
calcium
channel blockers, or any beta-blocker
agents.
Tell your doctor if you are taking any
other medic

Ciri produk

APO-PROPRANOLOL
PROPRANOLOL TABLETS HCI 10MG AND 40MG
BETA-ADRENERGIC RECEPTOR BLOCKING AGENT
PHARMACOLOGY:
Propranolol is a beta-adrenergic receptor blocking agent. When access
to beta-adrenergic receptor sites is
blocked by propranolol, the chronotropic, inotropic, and vasodilator
responses to beta-adrenergic stimulation are
decreased proportionately. Beta-adrenergic blockade is useful in some
clinical conditions in which sympathetic
activity is excessive or inappropriate, and, therefore, detrimental to
the patient. Sympathetic stimulation is
however, vital in some situations, (e.g., in patients with AV block or
with a severely damaged heart) and should
be preserved. The basic objective of beta-adrenergic blockade is to
decrease adverse sympathetic stimulation but
not to the degree that impairs necessary sympathetic support.
Beta-blockade results in bronchial constriction by
interfering with endogenously or exogenously induced bronchodilation
(see Contraindications and Warnings).
The mechanism of the antihypertensive effects of propranolol has not
been established. Among the factors that
may be involved are: decreased cardiac output; inhibition of renin
release by the kidneys; and, diminution of
tonic sympathetic nerve outflow from vasomotor centres in the brain.
It has been suggested, but not established,
that propranolol may achieve a better antihypertensive effect in
patients with normal or elevated plasma renin
activity than those with low PRA. Propranolol may reduce the oxygen
requirement of the heart at any level of
effort by blocking catecholamine-induced increases in the heart rate,
systolic blood pressure, and the velocity
and extent of myocardial contraction. On the other hand, the drug may
increase oxygen requirements by
increasing left ventricular fiber length, and diastolic pressure, and
systolic ejection period. When the net effect is
beneficial in anginal patients, it manifests during exercise or stress
by delaying the onset of pain and reducing the
incidence and severity of anginal attacks. Prop