ANTIHIST SYRUP 4MG5ML

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

CHLORPHENIRAMINE MALEATE

Boleh didapati daripada:

PAHANG PHARMACY SDN. BHD.

INN (Nama Antarabangsa):

CHLORPHENIRAMINE MALEATE

Unit dalam pakej:

120 ml mL; 60 ml mL

Dikeluarkan oleh:

Noripharma Sdn. Bhd.

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
ANTIHIST SYRUP
Chlorpheniramine maleate (4mg/5ml
)
1
WHAT IS IN THIS LEAFLET
1.
What Antihist Syrup is used for
2.
How Antihist Syrup works
3.
Before you take Antihist Syrup
4.
How to take Antihist Syrup
5.
While you are using Antihist Syrup
6.
Side effects
7.
Storage
and
Disposal
of
Antihist
Syrup
8.
Product Description
9.
Manufacturer and Product registration
holder
10.
Date of Revision
WHAT ANTIHIST SYRUP IS USED FOR
Antihist Syrup is used to treat problems
caused by allergies, such as hay fever,
itchy
skin,
swelling,
food
allergy,
reactions to medicines, or insect bites.
HOW ANTIHIST SYRUP WORKS
Antihist Syrup contains the active
ingredient
chlorpheniramine
maleate.
Chlorpheniramine is an antihistamine,
which blocks the action of histamine
in the body and relieves swelling,
itching, mucus production, and other
symptoms of allergy.
BEFORE YOU TAKE ANTIHIST SYRUP
Do not give this medicine: to children
below 2 years old. For children between 2
to 6 years old, this medicine should be
used
caution
and
following
the
advice
given by your doctor or pharmacist.
-
_When you must not take it _
Do not take this medicine if :

you are allergic to chlorpheniramine or
any other ingredients of this medicine
(listed in Product Description)

you are taking, or have taken in the past
two
weeks,
medicines for depression
called
Monoamine
oxidase
inhibitors
(MAOIs).
-
_Before you start to take it _
PREGNANCY AND BREAST-FEEDING
Please consult your doctor or pharmacist
if
you
are
pregnant,
planning
for
pregnancy, or breast-feeding before using
any medicine.
Chlorpheniramine may be secreted into
breast milk and may affect your baby.
Your doctor will discuss the risks and
benefits of breast feeding while you’re
taking Antihist Syrup.
-
_Taking other medicines _
Before you take this medicine, make sure
that you tell your doctor or pharmacist
about any other medicines you might be
using at the same time, particularly the
following:

medicines to help you relax (hypnotics
or an

Ciri produk

ANTIHIST SYRUP
DESCRIPTION:
A Clear, Orange liquid.
COMPOSITION:
Each 5 ml contains 4 mg Chlorpheniramine Maleate BP.
PHARMACODYNAMICS:
Chlorphenamine is a potent antihistamine (H
1
-antagonist).
Antihistamines diminish or abolish the actions of histamine in the
body by competative reversible blockade
of histamine H
1
-receptor sites on tissues. Chlorphenamine also has anticholinergic
activity.
Antihistamines act to prevent the release of histamine, prostaglandins
and leukotrines and have been shown
to prevent the migration of inflammatory mediators. The actions of
chlorphenmine include inhibition of
histamine on smooth muscle, cappillary permeability and hence
reduction of oedema and wheal in
hypersensitivity reactions such as allergy and anaphylaxis.
PHARMACOKINETICS:
Chlorphenamine is well absorbed from the gastro-intestinal tract,
following oral administration. The effects
develop within 30 minutes, are maximal within I to 2 hours and last 4
to 6 hours. The plasma half-life has
been estimated to be 12 to 15 hours.
Chlorphenamine is metabolised to the monodesmethyl and didesmethyl
derivatives. About 22% of an oral
dose is excreted unchanged in the urine.
INDICATIONS:
Antihist Syrup (Chlorpheniramine Maleate) is a member of the
alkylamine group of antihistamines,
which are among the most active histamine antagonists available. It
has a wide safety margin and a very
low incidence of side-effects such as drowsiness and dizziness.
Symptomatic control of all allergic conditions responsive to
antihistamines including: Hay fever,
vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy,
drug and serum reactions, pruritis ani et
vulvae and insect bites.
WARNING:
Not suitable to be used in children below 2 years old.
For children between 2 to 6 years old — use with caution and follow
the advice given by the doctor or
pharmacist.
PRECAUTIONS:
All antihistamines, given in effective dosage, may cause dizziness or
drowsiness. In consequence, until
the effect of the treatment is known, patients treated with Antih