SODIUM CHLORIDE- sodium chloride injection

Valsts: Amerikas Savienotās Valstis

Valoda: angļu

Klimata pārmaiņas: NLM (National Library of Medicine)

Aktīvā sastāvdaļa:

SODIUM CHLORIDE (UNII: 451W47IQ8X) (SODIUM CATION - UNII:LYR4M0NH37, CHLORIDE ION - UNII:Q32ZN48698)

Pieejams no:

REMEDYREPACK INC.

Ievadīšanas:

INTRAVENOUS

Receptes veids:

PRESCRIPTION DRUG

Ārstēšanas norādes:

Sodium Chloride Injection, USP, 0.9% preparations are indicated for diluting or dissolving drugs for intramuscular, intravenous or subcutaneous injection according to instructions of the manufacturer of the drug to be administered. Sodium Chloride Injection, USP, 0.9% is also indicated for use in flushing of intravenous catheters.

Produktu pārskats:

Sodium Chloride Injection, USP, 0.9%, preservative free, is available as follows:  Single dose vials, packaged 25 vials per tray. Preservative Free .   Discard unused portion. Use only if solution is clear and seal intact. Store at 20º to 25ºC (68º to 77ºF) [see USP Controlled Room Temperature]. *Vial stoppers do not contain natural rubber latex.

Autorizācija statuss:

Abbreviated New Drug Application

Produkta apraksts

SODIUM CHLORIDE- SODIUM CHLORIDE INJECTION
REMEDYREPACK INC.
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SODIUM CHLORIDE INJECTION, USP
0.9%
DESCRIPTION:
Sodium Chloride Injection, USP, 0.9% is a sterile, nonpyrogenic
solution. The osmolarity is 300
mOsmol per liter (calculated).
Each mL contains: Sodium chloride 9 mg; Water for Injection q.s. It
contains no bacteriostat,
antimicrobial agent or added buffer and is supplied only in single
dose containers. Hydrochloric acid
and/or sodium hydroxide may have been added for pH adjustment (pH
4.5-7.0).
Sodium chloride occurs as colorless cubic crystals or white
crystalline powder and has a saline taste.
Sodium chloride is freely soluble in water. It is soluble in glycerin
and slightly soluble in alcohol.
The empirical formula for sodium chloride is NaCl and the molecular
weight is 58.44.
CLINICAL PHARMACOLOGY:
Sodium chloride in water dissociates to provide sodium (Na
) and chloride (Cl
) ions. These ions
are normal constituents of the body fluids (principally extracellular)
and are essential for maintaining
electrolyte balance.
The distribution and excretion of sodium (Na
) and chloride (Cl
) are largely under the control of the
kidney which maintains a balance between intake and output.
The small volume of fluid and amount of sodium chloride provided by
Sodium Chloride Injection, USP,
0.9%, when used only as a vehicle for parenteral injection of drugs,
is unlikely to exert a significant
effect on fluid and electrolyte balance except possibly in very small
infants.
Water is an essential constituent of all body tissues and accounts for
approximately 70% of total body
weight. Average normal adult daily requirement ranges from two to
three liters (1 to 1.5 liters each for
insensible water loss by perspiration and urine production).
Water balance is maintained by various regulatory mechanisms. Water
distribution depends primarily on
the concentration of electrolytes in the body compartments and sodium
(Na
) plays a major role in
maintaining physiologic equilibrium.
INDICATIONS AND USAGE:
Sodium Chloride