MEDICATED DNA COLLECTION KIT- lidocaine hydrochloride, glycerin solution

Valsts: Amerikas Savienotās Valstis

Valoda: angļu

Klimata pārmaiņas: NLM (National Library of Medicine)

Aktīvā sastāvdaļa:

LIDOCAINE HYDROCHLORIDE ANHYDROUS (UNII: EC2CNF7XFP) (LIDOCAINE - UNII:98PI200987)

Pieejams no:

TrueFit RX LLC

SNN (starptautisko nepatentēto nosaukumu):

LIDOCAINE HYDROCHLORIDE ANHYDROUS

Kompozīcija:

LIDOCAINE HYDROCHLORIDE ANHYDROUS 20 mg in 1 mL

Ievadīšanas:

ORAL

Receptes veids:

PRESCRIPTION DRUG

Ārstēšanas norādes:

Lidocaine Ointment 2% is indicated for production of anesthesia of accessible mucous membranes of the oropharynx. Lidocaine is contraindicated in patients with a known history of hypersensitivity to local anesthetics of the amide type or to other components of Lidocaine Ointment 2%.

Produktu pārskats:

Lidocaine Hydrochloride Oral Topical Solution, USP (Viscous) 2% is a clear, viscous liquid with a very slight orange flavor available in 100 mL polyethylene squeeze bottles and in 15 mL unit dose in trays of ten cups. The solution should be stored at controlled room temperature 15° - 30°C (59° - 86°F). SHAKE WELL BEFORE USE. Manufactured by: Hi-Tech Pharmacal Co., Inc. Amityville, NY 11701 Made in U.S.A. Rev. 775:07 03/15

Autorizācija statuss:

Abbreviated New Drug Application

Produkta apraksts

MEDICATED DNA COLLECTION KIT- LIDOCAINE HYDROCHLORIDE, GLYCERIN
SOLUTION
TRUEFIT RX LLC
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MEDICATED DNA COLLECTION KIT
A Topical Anesthetic for the Mucous Membranes of the Mouth and
Pharynx.
For Oral Use Only.
Rx Only
Lidocaine Ointment 2% contains a local anesthetic agent and is
administered topically.
See INDICATIONS AND USAGE for specific uses.
Lidocaine Ointment 2% contains lidocaine, which is chemically
designated as acetamide, 2-
(diethylamino)-N-(2,6-dimethylphenyl)-, and has the following
structural formula: C
H
N
Molecular Weight 234.34
Composition of Lidocaine Ointment 2%: acetamide,
2-(diethylamino)-N-(2,6-dimethylphenyl)-,
(lidocaine) 2% in a water miscible ointment vehicle containing
polyethylene glycols and peppermint oil.
MECHANISM OF ACTION
Conduction of impulses, thereby effecting local anesthetic action.
ONSET OF ANESTHESIA
Lidocaine Ointment 2% effects local, topical anesthesia. The onset of
action is 3-5 minutes. It is
ineffective when applied to intact skin.
HEMODYNAMICS
Excessive blood levels may cause changes in cardiac output, total
peripheral resistance, and mean
arterial pressure. These changes may be attributable to a direct
depressant effect of the local anesthetic
agent on various components of the cardiovascular system.
PHARMACOKINETICS AND METABOLISM
Lidocaine may be absorbed following topical administration to mucous
membranes, its rate and extent of
absorption depending upon the specific site of application, duration
of exposure, concentration, and
total dosage. In general, the rate of absorption of local anesthetic
agents following topical application
occurs most rapidly after intratracheal administration. Lidocaine is
also well-absorbed from the
14
22
2O
gastrointestinal tract, but little intact drug appears in the
circulation because of biotransformation in the
liver.
Lidocaine is metabolized rapidly by the liver, and metabolites and
unchanged drug are excreted by the
kidneys. Biotransformation includes oxidative N-dealkylation, ring
hydroxylation, cleavage of the amid