Mannitol 75g/500ml (15%) infusion Viaflo bags

Valsts: Lielbritānija

Valoda: angļu

Klimata pārmaiņas: MHRA (Medicines & Healthcare Products Regulatory Agency)

Aktīvā sastāvdaļa:

Mannitol

Pieejams no:

15%) infusion Viaflo bags (Baxter Healthcare Ltd

SNN (starptautisko nepatentēto nosaukumu):

Mannitol

Deva:

150mg/1ml

Zāļu forma:

Infusion

Ievadīšanas:

Intravenous

Klase:

No Controlled Drug Status

Receptes veids:

Valid as a prescribable product

Produktu pārskats:

BNF: ; GTIN: 5413760373096

Produkta apraksts

OBJECT 1
MANNITOL 15% W/V SOLUTION FOR INFUSION
Summary of Product Characteristics Updated 08-Feb-2018 | Baxter
Healthcare Ltd
1. Name of the medicinal product
Mannitol 15% w/v Solution for infusion
2. Qualitative and quantitative composition
Mannitol: 150 g/l
Each ml contains 150 mg mannitol.
For the full list of excipients, see section 6.1.
3. Pharmaceutical form
Solution for Infusion
Clear, colourless solution, free from visible particles.
Osmolarity: 823 mOsm/l (approx)
pH: 4.5- 7.0
4. Clinical particulars
4.1 Therapeutic indications
Mannitol 15% w/v Solution for infusion is indicated for use as an
osmotic diuretic in the following
situations:
• Promotion of diuresis in the prevention and/or treatment of the
oliguric phase of acute renal failure
before irreversible oliguric renal failure becomes established.
• Reduction of intracranial pressure and cerebral oedema, when the
blood-barrier is intact.
• Reduction of elevated intraocular pressure when it cannot be
lowered by other means.
• Promotion of elimination of renally excreted toxic substances in
poisoning.
4.2 Posology and method of administration
Posology:
The choice of the specific mannitol concentration, dosage and rate of
administration depends on the age,
weight and clinical condition of the patient and concomitant therapy.
Adults and adolescents:
Acute renal failure
The general dose range for adults is 50 to 200 g mannitol (330 to 1320
ml) in a 24-hour period, with a
dosage limit of 50 g mannitol (330 ml) on any one occasion. In most
instances adequate response will be
achieved at a dosage of 50 to 100 g mannitol/day (330 to 660 ml). The
rate of administration is usually
adjusted to maintain a urine flow of at least 30-50 ml per hour.
Only in emergency situations, the maximum infusion rate can be as high
as 200 mg/kg infused over 5
minutes (see also test dose). After 5 minutes, the infusion rate
should be readjusted to maintain a urine
flow of at least 30-50 ml per hour, with a maximum dose of 200 g/24h.
_Use in patients with oliguria or ren