LIDOCAINE HCL AND HYDROCORTISONE ACETATE hydrochloride cream

Valsts: Amerikas Savienotās Valstis

Valoda: angļu

Klimata pārmaiņas: NLM (National Library of Medicine)

Aktīvā sastāvdaļa:

LIDOCAINE HYDROCHLORIDE (UNII: V13007Z41A) (LIDOCAINE - UNII:98PI200987)

Pieejams no:

Acella Pharmaceuticals, LLC

SNN (starptautisko nepatentēto nosaukumu):

LIDOCAINE HYDROCHLORIDE

Kompozīcija:

LIDOCAINE HYDROCHLORIDE ANHYDROUS 30 mg in 1 g

Receptes veids:

PRESCRIPTION DRUG

Autorizācija statuss:

unapproved drug other

Produkta apraksts

LIDOCAINE HCL AND HYDROCORTISONE ACETATE- LIDOCAINE HYDROCHLORIDE AND
HYDROCORTISONE ACETATE CREAM
ACELLA PHARMACEUTICALS, LLC
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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LIDOCAINE HCL 3% - HYDROCORTISONE ACETATE 0.5% CREAM
DESCRIPTION:
Anti-Inflammatory Anesthetic for Relief of Hemorrhoid Pain, Swelling
and Inflammation.
Lidocaine is chemically designated as acetamide,
2-(diethylamino)-N-(2,6-dimethylphenyl), and has the
following structure:
Hydrocortisone acetate has a chemical name pregn-4-ene-3, 20-dione,
21-(acetyloxy)-11, 17-
dihydroxy-(11ß)-, and has the following structural formula:
INGREDIENTS: LIDOCAINE HCL 3% - HYDROCORTISONE ACETATE 0.5% CREAM
Each gram contains Lidocaine HCl 30 mg, Hydrocortisone Acetate 5 mg.
ACTIVE INGREDIENTS:
LIDOCAINE HCl 3%
HYDROCORTISONE ACETATE 0.5%
INACTIVE INGREDIENTS:
Purified Water, Propylene Glycol, Glyceryl Stearate (and) PEG-100
Stearate, Cetyl Alcohol, Stearyl
Alcohol, Petrolatum, Mineral Oil, PEG 150 Distearate, Xanthan Gum,
Methyl Paraben, Polycarbophil,
Sodium Citrate, Aluminum Sulfate, Calcium Acetate, Sodium Hydroxide,
Propyl Paraben, Citric Acid
CLINICAL PHARMACOLOGY:
MECHANISM OF ACTION:
Product releases lidocaine to stabilize the neuronal membrane by
inhibiting the ionic fluxes required for
initiation and conduction of impulses, thereby effecting local
anesthetic action. Hydrocortisone acetate
provides relief of inflammatory and pruritic manifestations of
corticosteroid responsive dermatoses.
PHARMACOKINETICS:
Lidocaine may be absorbed following topical administration to mucous
membranes, its rate and extent of
absorption depending upon the specific site of application, duration
of exposure, concentration, and
total dosage. In general, the rate of absorption of local anesthetic
agents following topical application
occurs most rapidly after intratracheal administration. Lidocaine is
also well-absorbed from the