Latanoprost Pfizer

Valsts: Austrālija

Valoda: angļu

Klimata pārmaiņas: Department of Health (Therapeutic Goods Administration)

Aktīvā sastāvdaļa:

Latanoprost

Pieejams no:

Pfizer Australia Pty Ltd

Klase:

Medicine Registered

Lietošanas instrukcija

LATANOPROST PFIZER
®

_EYE DROPS_
_Latanoprost_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Latanoprost Pfizer. It
does not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using Latanoprost
Pfizer against the benefits it is
expected to have for you.
IF YOU HAVE ANY CONCERNS ABOUT
USING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE MEDICINE.
You may need to read it again.
WHAT LATANOPROST
PFIZER IS USED FOR
Latanoprost Pfizer is used to lower
raised pressure in the eye and to treat
glaucoma. Glaucoma is a condition
in which the pressure of fluid in the
eye may be high. However, some
people with glaucoma may have
normal eye pressure.
Glaucoma is usually caused by a
build up of the fluid which flows
through the eye. This build up occurs
because the fluid drains out of your
eye more slowly than it is being
pumped in. Since new fluid continues
to enter the eye, joining the fluid
already there, the pressure continues
to rise. This raised pressure may
damage the back of the eye resulting
in gradual loss of sight. Damage can
progress so slowly that the person is
not aware of this gradual loss of
sight. Sometimes even normal eye
pressure is associated with damage to
the back of the eye.
There are usually no symptoms of
glaucoma. If glaucoma is not treated
it can lead to serious problems,
including total blindness. In fact,
untreated glaucoma is one of the
most common causes of blindness.
_HOW LATANOPROST PFIZER_
_WORKS_
Latanoprost Pfizer belongs to a
family of medicines called
prostaglandin agonists.
It lowers the pressure in the eye by
allowing more fluid to flow out from
within your eye.
Although Latanoprost Pfizer helps
control your glaucoma it does not
cure it. So you must keep using it
until your doctor tells you to stop.
Latanoprost Pfizer is used, either
alone or in combination

Produkta apraksts

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PRODUCT INFORMATION 
LATANOPROST PFIZER
®
 EYE DROPS 
(LATANOPROST 50 MICROGRAMS/ML) 
NAME OF THE MEDICINE 
LATANOPROST  
OH
OH
OH
COOCH(CH
3
)
2

The chemical name of latanoprost is Isopropyl-(Z)-7[(1R,2R,3R,5S) 3,5-dihydroxy-2-
[(3R)-3-hydroxy-5-phenyl-1-pentyl]cyclopentyl]-5-heptenoate,  according  to  IUPAC.  
Its  molecular  formula  is  C
26
H
40
O
5
  and  its  molecular  weight  is  432.58.    The  CAS 
number for latanoprost is 130209-82-4. 
DESCRIPTION 
The active ingredient in LATANOPROST PFIZER is latanoprost, a prostaglandin
F
2

analogue.  Latanoprost  is  a viscous oil which is practically insoluble in water, freely 
soluble in ethanol, ethyl acetate, isopropanol, methanol, acetone and octanol, and very 
soluble in acetonitrile. 
Sixty  four  isomers  of  latanoprost  are  possible,  however,  for  LATANOPROST 
PFIZER it is purified as a single isomer. 
LATANOPROST  PFIZER  Eye  Drops  is  a  sterile,  isotonic  solution  containing  50 
micrograms/mL  of  latanoprost  in  an  aqueous  buffer  solution  of  pH  6.7.    The 
excipients  in  LATANOPROST  PFIZER  are  sodium  chloride,  monobasic  sodium 
phosphate,  dibasic  anhydrous  sodium  phosphate,  water  for  injections  and 
benzalkonium chloride (0.20 mg/mL) as a preservative agent. 
The solution is a clear and colourless liquid, filled in a
polyethylene container. 
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PHARMACOLOGY 
PHARMACOKINETICS 
Latanoprost is an isopropyl ester pro drug which is inactive, but after hydrolysis to the 
acid of latanoprost, becomes biologically active. 
The pro drug is well absorbed through the cornea and all drug that enters the aqueous 
humour is hydrolysed during the passage through the