IVERMECTIN PLUS- ivermectin and clorsulon injection

Valsts: Amerikas Savienotās Valstis

Valoda: angļu

Klimata pārmaiņas: NLM (National Library of Medicine)

Aktīvā sastāvdaļa:

IVERMECTIN (UNII: 8883YP2R6D) (IVERMECTIN - UNII:8883YP2R6D), CLORSULON (UNII: EG1ZDO6LRD) (CLORSULON - UNII:EG1ZDO6LRD)

Pieejams no:

Durvet, Inc.

Ievadīšanas:

SUBCUTANEOUS

Receptes veids:

OTC

Ārstēšanas norādes:

INDICATIONS Ivermectin Plus is indicated for the effective treatment and control of the following parasites in cattle: Gastrointestinal Roundworms  (adults and fourth-stage larvae): Ostertagia ostertagi  (including inhibited O. ostertagi ) O. lyrata Haemonchus placei Trichostrongylus axei T. colubriformis Cooperia oncophora C. punctata C. pectinata Bunostomum phlebotomum Nematodirus helvetianus  (adults only) N. spathiger  (adults only) Oesophagostomum radiatum Lungworms  (adults and fourth-stage larvae): Dictyocaulus viviparus Liver Flukes: Fasciola hepatica  (adults only) Cattle Grubs  (parasitic stages): Hypoderma bovis H. lineatum Sucking Lice: Linognathus vituli Haematopinus eurysternus Solenopotes capillatus Mange Mites  (Cattle Scab*): Psoroptes ovis  (syn. P. communis  var. bovis) Sarcoptes scabiei  var. bovis Persistent Activity Ivermectin and clorsulon injection has been proved to effectively control infections and to protect cattle from reinfection with Dictyocaulus viviparu

Produktu pārskats:

HOW SUPPLIED Ivermectin Plus is available in three ready-to-use sizes: The 250 mL plastic bottle is suitable for use with automatic syringe equipment. Each bottle contains sufficient solution to treat 50 head of 550 lb (250 kg) cattle. The 500 mL plastic bottle is suitable for use with automatic syringe equipment. Each bottle contains sufficient solution to treat 100 head of 550 lb (250 kg) cattle. The 1000 mL plastic bottle is suitable for use with automatic syringe equipment. Each bottle contains sufficient solution to treat 200 head of 550 lb (250 kg) cattle.

Autorizācija statuss:

Abbreviated New Animal Drug Application

Produkta apraksts

IVERMECTIN PLUS- IVERMECTIN AND CLORSULON INJECTION
DURVET, INC.
----------
APPROVED BY FDA UNDER ANADA # 200-450
RESTRICTED DRUG (CALIFORNIA)- USE ONLY AS DIRECTED.
LVERMECTIN PLUS
(IVERMECTIN AND CLORSULON)
INJECTION FOR CATTLE
FOR THE EFFECTIVE TREABNENT AND CONTROLOF INTERNAL PARASITES,
INCLUDING ADULT LIVER FLUKES,
AND EXTERNAL PARASITES.
CONSULT YOUR VETERINARIAN FOR ASSISTANCE IN THE DIAGNOSIS, TREATMENT
AND CONTROL OF PARASITISM.
INTRODUCTION
The ability of ivermectin to deliver internal and external parasite
control has been proven in cattle
markets around the world. Now, lvermectin Plus combines ivermectin,
the active ingredient of
lvermectin 1%, with clorsulon, an effective adult flukicide.
A single injection of lvermectin Plus (ivermectin and clorsulon)
offers all the benefits of lvermectin 1%
plus control of adult _Fasciola hepatica_.
THE DOSAGE LEVEL OF CLORSULON SUPPLIED BY LVERRNECTIN PLUS IS
EFFECTIVE ONLY AGAINST ADULT LIVER
FLUKES (_FASCIOLA HEPATICA_).
PRODUCT DESCRIPTION
lvermectin Plus is a ready-to-use sterile solution containing 1% w/v
ivermectin, 10% w/v clorsulon,
40% glycerol formal, and propylene glycol, q.s. ad 100%. It is
formulated to deliver the recommended
dose level of 200 meg ivermectin/kg and 2 mg clorsulon/kg given
subcutaneously behind the shoulder
at the rate of 1 ml per 110 lb (50 kg) body weight.
MODE OF ACTION
lvermectin is a member of the macrocyclic lactone class of
endectocides which have a unique mode of
action. Compounds of the class bind selectively and with high affinity
to glutamate-gated chloride ion
channels which occur in invertebrate nerve and muscle cells. This
leads to an increase in the
permeability of the cell membrane to chloride ions with
hyperpolarization of the nerve or muscle cell,
resulting in paralysis and death of the parasite. Compounds of this
class may also interact with other
ligand-gated chloride channels, such as those gated by the
neurotransmitter gamma-aminobutyric acid
(GABA).
The margin of safety for compounds of this class is attributabl