Valsts: Amerikas Savienotās Valstis
Valoda: angļu
Klimata pārmaiņas: NLM (National Library of Medicine)
Heparin Sodium (UNII: ZZ45AB24CA) (Heparin - UNII:T2410KM04A)
General Injectables & Vaccines, Inc
Heparin Sodium
Heparin 5000 [USP'U] in 1 mL
INTRAVENOUS
PRESCRIPTION DRUG
Heparin Sodium Injection is indicated for: Anticoagulant therapy in prophylaxis and treatment of venous thrombosis and its extension; Low-dose regimen for prevention of postoperative deep venous thrombosis and pulmonary embolism in patients undergoing major abdominothoracic surgery or who, for other reasons, are at risk of developing thromboembolic disease (see DOSAGE AND ADMINISTRATION ); Prophylaxis and treatment of pulmonary embolism; Atrial fibrillation with embolization; Diagnosis and treatment of acute and chronic consumptive coagulopathies (disseminated intravascular coagulation); Prevention of clotting in arterial and cardiac surgery; Prophylaxis and treatment of peripheral arterial embolism. Heparin may also be employed as an anticoagulant in blood transfusions, extracorporeal circulation, and dialysis procedures and in blood samples for laboratory purposes. Heparin sodium should NOT be used in patients with the following conditions: Severe thrombocytopenia; When suitable blood coagulation test
Heparin Sodium Injection, USP (porcine) preservative free , is available as follows: Preservative Free Discard Unused Portion. Do not use if solution is discolored or contains a precipitate. Heparin Sodium Injection, USP (porcine) contains benzyl alcohol and is available as follows: Use only if solution is clear and seal intact. Heparin Sodium Injection, USP (porcine) contains parabens and is available as follows: *Packaged in a plastic or glass vial. **Packaged in a plastic vial. The above products are available in multiple dose, flip-top vials packaged in 25. Do not use if solution is discolored or contains a precipitate.
New Drug Application
HEPARIN SODIUM- HEPARIN SODIUM INJECTION, SOLUTION GENERAL INJECTABLES & VACCINES, INC ---------- HEPARIN SODIUM 5,000 UN/ML INJECTION, USP 1 ML MULTI DOSE VIAL DES CRIPTION Heparin is a heterogeneous group of straight-chain anionic mucopolysaccharides, called glycosaminoglycans, having anticoagulant properties. Although others may be present, the main sugars occurring in heparin are: (1) α-L-iduronic acid 2-sulfate, (2) 2-deoxy-2-sulfamino-α-D-glucose 6- sulfate, (3) ß-D-glucuronic acid, (4) 2-acetamido-2-deoxy-α-D-glucose and (5) α-L-iduronic acid. These sugars are present in decreasing amounts, usually in the order (2)greater than (1)greater than (4)greater than (3)greater than (5), and are joined by glycosidic linkages, forming polymers of varying sizes. Heparin is strongly acidic because of its content of covalently linked sulfate and carboxylic acid groups. In heparin sodium, the acidic protons of the sulfate units are partially replaced by sodium ions. Heparin Sodium Injection, USP is a sterile solution of heparin sodium derived from porcine intestinal mucosa, standardized for anticoagulant activity, in water for injection. It is to be administered by intravenous or deep subcutaneous routes. The potency is determined by a biological assay using a USP reference standard based on units of heparin activity per milligram. Structure of Heparin Sodium (representative subunits): Heparin Sodium Injection, USP (porcine), preservative free, is available as follows: Each mL of the 1,000 Units per mL preparation contains: 1,000 USP Heparin Units (porcine); 9 mg sodium chloride; Water for Injection q.s. Made isotonic with sodium chloride. Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (5.0-7.5). Heparin Sodium Injection, USP (porcine), preserved with benzyl alcohol, is available as follows: Each mL of the 5,000 Units per mL preparation contains: 5,000 USP Heparin Units (porcine); 6 mg sodium chloride; 15 mg benzyl alcohol (as a preservative); Water for Injection q.s. Hydrochloric a Izlasiet visu dokumentu