Valsts: Malaizija
Valoda: angļu
Klimata pārmaiņas: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
ORPHENADRINE CITRATE; Paracetamol
DUOPHARMA MANUFACTURING (BANGI) SDN BHD
ORPHENADRINE CITRATE; Paracetamol
100 Tablet Tablets; 30 Tablet Tablets; 500 Tablet Tablets; 1000 Tablet Tablets
DUOPHARMA MANUFACTURING (BANGI) SDN BHD
ANAREX TABLET Orphenadrine citrate / Paracetamol (35mg / 450mg) 1 _CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ WHAT IS IN THIS LEAFLET 1. What Anarex Tablet is used for 2. How Anarex Tablet works 3. Before you use Anarex Tablet 4. How to use Anarex Tablet 5. While you are using it 6. Side effects 7. Storage and Disposal of Anarex Tablet 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT ANAREX TABLET IS USED FOR Anarex Tablet is used to relieve mild to moderate pain and discomfort related to conditions that affect muscles and bones. Your doctor may have prescribed Anarex Tablet for another purpose. Ask your doctor if you have any questions about why this medicine has been prescribed for you. HOW ANAREX TABLET WORKS Orphenadrine citrate is a muscle relaxant. It acts in the nervous system to produce muscle relaxant effects. Paracetamol is used to treat or prevent pain and reduce fever. BEFORE YOU USE ANAREX TABLET - _When you must not use it _ Do not take Anarex Tablet if you have had an allergic reaction to orphenadrine citrate, paracetamol or other similar medicine, or to any of the ingredients listed at the end of this leaflet. _ _ Do not take Anarex Tablet if you have any of the following: • high pressure in the eye • obstruction of small intestine or stomach • stomach ulcer • failure of lower esophagus opening up during swallowing • enlarged prostate • obstructions at the bladder neck • myasthenia gravis (a disease of muscles causing drooping eyelids, double vision, difficulty in speaking and swallowing, and, sometimes muscle weakness in the arms or legs). Do not take Anarex Tablet: • after the expiry date on the pack; • if the packaging shows signs of tampering; • unless advised by your doctor Do not give this medicine to a child under the age of 12 years. Safety and effectiveness in children younger than 12 years have not been established. _ _ - _Before you start use it _ Tell your doctor or pharmacist if: • you have allergies to any ot Izlasiet visu dokumentu
Because of the mild anticholinergic effect of orphenadrine, Anarex should not be used in patients with glaucoma, duodenal or pyloric obstruction, stenosing peptic ulcer, achalasia, prostatic hypertrophy, or obstructions at the bladder neck. Anarex is also contraindicated in patients with myasthenia gravis and in patients known to be sensitive to paracetamol or orphenadrine. Anarex Tablet should be given with care to active alcoholics, and patients with hepatic diseases or viral hepatitis as there is an increased risk of hepatotoxicity. Risk of adverse renal effects may be increased with prolonged use of high doses of Anarex Tablet in patients with renal function impairment. It should be used cautiously in patients with cardiac disease, arrhythmias and tachycardia as ophenadrine may cause tachycardia. CNS depression may also be exarcebated. Blood count, hepatic and renal function determinations may be required at periodic intervals during prolonged or high-dose therapy since the safety of continuous long-term use has not been established. Paracetamol may cause falsely decreased values in blood glucose determinations when the glucose oxidase/peroxidase method is used, but probably not when the hexokinase/glucose-6-phosphate dehydrohenase (G6PD) method is used. Values may also be falsely increased when certain instruments are used in glucose analysis if high paracetamol concentrations are present. Paracetamol may cause false-positive results in qualitative screening tests of serum 5-Hydroxyindoleacetic acid (5-HIAA) using nitrosonaphthol reagent; the quantitative test is unaffected. Administration of paracetamol prior to the pancreatic function test using bentiromide will invalidate test results because paracetamol is also metabolized to an arylamine and will thus increase the apparent quantity of para-aminobenzoic acid (PABA) recovered; it is recommended that paracetamol be discontinued at least 3 days prior to administration of bentiromide. Falsely increased values are also obtained when the phosphotungstate uric Izlasiet visu dokumentu