VETROMAX- gentamicin sulfate, betamethasone valerate and clotrimazole ointment

Šalis: Jungtinės Valstijos

kalba: anglų

Šaltinis: NLM (National Library of Medicine)

Veiklioji medžiaga:

GENTAMICIN SULFATE (UNII: 8X7386QRLV) (GENTAMICIN - UNII:T6Z9V48IKG), BETAMETHASONE VALERATE (UNII: 9IFA5XM7R2) (BETAMETHASONE - UNII:9842X06Q6M), CLOTRIMAZOLE (UNII: G07GZ97H65) (CLOTRIMAZOLE - UNII:G07GZ97H65)

Prieinama:

Dechra Veterinary Products

INN (Tarptautinis Pavadinimas):

GENTAMICIN SULFATE

Sudėtis:

GENTAMICIN 3 mg in 1 g

Vartojimo būdas:

AURICULAR (OTIC)

Recepto tipas:

PRESCRIPTION

Terapinės indikacijos:

Vetromax ointment is indicated for the treatment of canine acute and chronic otitis externa associated with yeast (Malassezia pachydermatis, formerly Pityrosporum canis) and/or bacteria susceptible to gentamicin. If hypersensitivity to any of the components occurs, treatment should be discontinued and appropriate therapy instituted. Concomitant use of drugs known to induce ototoxicity should be avoided. Do not use in dogs with known perforation of eardrums.

Produkto santrauka:

Vetromax ointment is available in: 7.5 g NDC 17033-282-75 tubes 15 g NDC 17033-282-15 tubes

Autorizacija statusas:

Abbreviated New Animal Drug Application

Prekės savybės

VETROMAX- GENTAMICIN SULFATE, BETAMETHASONE VALERATE AND
CLOTRIMAZOLE OINTMENT
DECHRA VETERINARY PRODUCTS
----------
VETROMAX
GENTAMICIN SULFATE USP, BETAMETHASONE VALERATE USP AND CLOTRIMAZOLE
USP
OINTMENT
VETERINARY
ANADA# 200-283. Approved by FDA.
For otic use in dogs only.
CAUTION:
FEDERAL LAW RESTRICTS THIS DRUG TO USE BY OR ON THE ORDER OF A
LICENSED
VETERINARIAN.
KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.
DESCRIPTION:
Each gram of Vetromax ointment contains gentamicin sulfate USP
equivalent to 3 mg
gentamicin base; betamethasone valerate USP equivalent to 1 mg
betamethasone; and
10 mg clotrimazole USP in a mineral oil-based system containing a
plasticized
hydrocarbon gel.
PHARMACOLOGY:
GENTAMICIN: Gentamicin sulfate is an aminoglycoside antibiotic active
against a wide
variety of pathogenic gram-negative and gram-positive bacteria. _In
vitro_ tests have
determined that gentamicin is bactericidal and acts by inhibiting
normal protein synthesis
in susceptible microorganisms. Specifically, gentamicin is active
against the following
organisms commonly isolated from canine ears: _Staphylococcus aureus,_
other
_Staphylococcus_ spp., _Pseudomonas aeruginosa, Proteus_ spp., and
_Escherichia coli._
BETAMETHASONE: Betamethasone valerate is a synthetic adrenocorticoid
for
dermatologic use. Betamethasone, an analog of prednisolone, has a high
degree of
corticosteroid activity and a slight degree of mineralocorticosteroid
activity.
Betamethasone valerate, the 17-valerate ester of betamethasone, has
been shown to
provide anti-inflammatory and antipruritic activity in the topical
management of
corticosteroid-responsive otitis externa.
Topical corticosteroids can be absorbed from normal, intact skin.
Inflammation can
increase percutaneous absorption. Once absorbed through the skin,
topical
corticosteroids are handled through pharmacokinetic pathways similar
to systemically
administered corticosteroids.
CLOTRIMAZOLE: Clotrimazole is a broad-spectrum antifungal agent that
is used for the
treatment of dermal infec