Stenac Effervescent Tablets 600 mg

Šalis: Malaizija

kalba: anglų

Šaltinis: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Veiklioji medžiaga:

Acetylcysteine

Prieinama:

APEX PHARMACY MARKETING SDN. BHD.

INN (Tarptautinis Pavadinimas):

Acetylcysteine

Vienetai pakuotėje:

30 Tablets

Pagaminta:

SYNMOSA BIOPHARMA CORPORATION

Pakuotės lapelis

_Consumer Medication Information Leaflet (RiMUP) _
STENAC EFFERVESCENT TABLETS 600MG
ACETYLCYSTEINE (600MG)
1
WHAT IS IN THIS LEAFLET
1.
What
Stenac
Effervescent
Tablets 600 mg is used for
2.
How
Stenac
Effervescent
Tablets 600 mg works
3.
Before
you
use
Stenac
Effervescent
Tablets
600
mg
4.
How
to
use
Stenac
Effervescent
Tablets
600
mg
5.
While you are using Stenac
Effervescent
Tablets
600
mg
6.
Side effects
7.
Storage
and
disposal
of
Stenac
Effervescent
Tablets 600 mg
8.
Product description
9.
Manufacturer and Product
registration holder
10.
Date of revision
WHAT STENAC EFFERVESCENT TABLETS
600MG IS USED FOR
Stenac Effervescent Tablets 600mg
are used:
a.
to
reduce
the
thickness
of
secretions from the respiratory tract
b. as an antidote for overdose of the
medication 'acetaminophen'.
(If you have consumed too much
'acetaminophen', please see a doctor
immediately)
HOW STENAC EFFERVESCENT TABLETS
600MG WORKS
Stenac Effervescent Tablets 600 mg
contain Acetylcysteine.
Acetylcysteine
helps
to
reduce
thickness
of
the
mucus
in
the
respiratory
tract,
and
has
been
shown
to
dramatically
effect
in
sputum.
BEFORE
YOU
USE
STENAC
EFFERVESCENT TABLETS 600MG
_- When you must not use it _

You are children below two years
of age.

You know that you are allergic to
Acetylcysteine.

You have inherited disorder that
causes
an
amino
acid
called
phenylalanine to build up in your
body
or
you
are
allergic
to
aspartame (artificial sweetener).
_- Before you start to use it_
Patients
with
asthma
should
be
carefully monitored. Treatment with
acetylcysteine
should
be
stopped
when
breathing
difficulties
occur.
The
sulfur
odour
on
opening
the
sachets
does
not
indicate
deterioration of the product, but is
due to the active ingredient.
Other medicines should not be used
with acetylcysteine solution.
Tell your doctor if you are pregnant,
or
plan
to
become
pregnant
or
breastfeeding.
Your
doctor
will
discuss
with
you
the
risks
and
benefits involved.
_- Taking other medicines_
Please
tell
your
doctor
or
pharmacist
if
you
are
taking
or
havi

Prekės savybės

COMPOSITION
Each tablet contains :
Acetylcysteine
……………………………………………………………………
600 mg
DESCRIPTION
White to light yellow, round, flat-faced tablets, embossed with
“
SYN
”
on one side.
INDICATIONS
Reduce the viscosity of the secretion of mucous membrane of
respiratory tract.
Antidotes for acute poisoning: Acetaminophen overdose.
ACTIONS (PHARMACODYNAMIC)
Acetylcysteine is the main active composition in the effervescent
tablets, through directly interaction with
mucoprotein complex and nucleic acid then to disrupt the mucoprotein
of phlegm into smaller clear units and
thereby reduces the viscosity of the phlegm. Acetylcysteine as a
mucolytic agent results from its sulfhydryl
interacting with disulfide bonds in mucoprotein, with the mucus
subsequently being broken into less viscous
units.
Acetylcysteine, an antioxidant, with active free sulfahydryl group can
interact with reactive oxygen species.
Acetylcysteine have a therapeutic application in preventing oxidative
tissue injury induced by hypochlorous
acid (HOCl). HOCl is toxic to cells because it initiates oxidative
injury and causes the activation of phagocyte
peroxidases, such as the neutrophil enzyme MPO. Acetylcysteine has
been shown to dramatically reduce the
viscosity and tenacity of sputum. The liquefying action is due to the
presence of a free sulphydryl group which
opens up disulphide bonds present in mucus. Pretreatment with
Acetylcysteine may prevent lung injury by
diminishing elastase activity; this diminished activity of elastase
may be achieved by enhanced inactivation by
antiproteases.
It is concluded that acetylcysteine is useful for viscosity and
maturative secretion of phlegm induced by acute
and chronic respiratory system inflammation. In addition, the
structure of acetylcysteine can transport through
cell membrane and decompose to L-cysteine, the main component of
glutathione (GSH), and maintains
cellular GSH at a level. GSH, an antioxidant, protects cells from
toxins such as free radicals.
A