Šalis: Indonezija
kalba: indoneziečių
Šaltinis: Badan Pengawas Obat dan Makanan RI - Indonesian Food and Drug Supervisory Agency
ERTAPENEM SODIUM
ORGANON PHARMA INDONESIA TBK - Indonesia
ERTAPENEM SODIUM
1213.00 MG
SERBUK INJEKSI
DUS, 1 VIAL @ 1 GRAM
ORGANON PHARMA INDONESIA TBK - Indonesia
2021-09-11
_ _ INVANZ (Ertapenem for Injection) THERAPEUTIC CLASS INVANZ (Ertapenem for Injection) is a sterile, synthetic, long-acting, parenteral, 1-β methyl- carbapenem that is structurally related to beta-lactam antibiotics, such as penicillins and cephalosporins, with activity against a wide range of gram-positive and gram-negative aerobic and anaerobic bacteria. MICROBIOLOGY Ertapenem has in vitro activity against a wide range of gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of ertapenem results from the inhibition of cell wall synthesis and is mediated through ertapenem binding to penicillin binding proteins (PBPs). In Escherichia coli , it has strong affinity toward PBPs 1a, 1b, 2, 3, 4 and 5 with preference for PBPs 2 and 3. Ertapenem has significant stability to hydrolysis by most classes of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases, but not metallo-beta-lactamases. INVANZ has been shown to be active against most strains of the following microorganisms in vitro and in clinical infections (see INDICATIONS): AEROBIC AND FACULTATIVE ANAEROBIC GRAM-POSITIVE MICROORGANISMS: Staphylococcus aureus (including penicillinase-producing strains) Streptococcus agalactiae Streptococcus pneumoniae Streptococcus pyogenes Note: Methicillin-resistant staphylococci are resistant to INVANZ. Many strains of Enterococcus faecalis and most strains of Enterococcus faecium are resistant. AEROBIC AND FACULTATIVE ANAEROBIC GRAM-NEGATIVE MICROORGANISMS: DISETUJUI OLEH BPOM : 02/08/2021 ID : EREG100373VR12100079 EREG100373VR12100080 _ _ Escherichia coli Haemophilus influenzae (including beta-lactamase producing strains) Klebsiella pneumoniae Moraxella catarrhalis Proteus mirabilis ANAEROBIC MICROORGANISMS: Bacteroides fragilis and other species in the B. fragilis Group Clostridium species (excluding C. difficile ) Eubacterium species Peptostreptococcus species Porphyromonas asaccharolytica Prevotella species. The following in vitro data a Perskaitykite visą dokumentą