Šalis: Australija
kalba: anglų
Šaltinis: Department of Health (Therapeutic Goods Administration)
donepezil hydrochloride
Amneal Pharma Australia Pty Ltd
Donepezil hydrochloride
Registered
_Donepezil AN tablets – Consumer Medicine Information _ _ _ _Doc ID: 110.AN.M.1.0 _ _ _ _ _ _Page 1 _ DONEPEZIL AN TABLETS _Donepezil hydrochloride _ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Donepezil AN. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking Donepezil AN against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT USING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT DONEPEZIL AN IS USED FOR Donepezil AN is used to treat mild, moderate and severe Alzheimer’s disease, also called dementia of the Alzheimer’s type. Donepezil AN will not cure this disease, but should help your memory and improve your thinking capacity. This medicine belongs to a group of medicines called acetylcholinesterase inhibitors. They are thought to work by increasing the level of a chemical called acetylcholine in the brain. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY THIS MEDICINE HAS BEEN PRESCRIBED FOR YOU. Your doctor may have prescribed it for another reason. This medicine is not addictive. This medicine is only available with a doctor's prescription. Before you take. BEFORE YOU TAKE DONEPEZIL AN _WHEN YOU MUST NOT TAKE _ _IT: _ _ _ DO NOT TAKE DONEPEZIL AN IF YOU HAVE AN ALLERGY TO: any medicine containing donepezil hydrochloride piperidine derivatives any of the ingredients listed at the end of this leaflet. Some of the symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin. DO NOT GIVE DONEPEZIL AN TO CHILDREN. The safety and effectiveness of Donepezil AN in children have not been established. DO NOT TAKE THIS MEDICINE AFTER THE EXPIRY DATE PRINTED Perskaitykite visą dokumentą
_Donepezil AN tablets Product Information _ _ _ _Amneal Pharma Australia Pty Ltd _ Donepezil AN PI v3.0 Page 1 DONEPEZIL AN _ _ _(DONEPEZIL HYDROCHLORIDE TABLETS) _ _ _ PRODUCT INFORMATION NAME OF THE MEDICINE The name of this medicine is Donepezil hydrochloride CHEMICAL NAME: (RS)-1-benzyl-4-[5,6-dimethoxy-1-indanon)-methylpiperidine hydrochloride MOLECULAR FORMULA: C 24 H 29 NO 3. HCl MOLECULAR WEIGHT: 415.96 CAS REGISTRY NUMBER: 120011-70-3 DESCRIPTION Donepezil hydrochloride is a specific and reversible inhibitor of the enzyme acetylcholinesterase. Donepezil hydrochloride is a white crystalline powder and is freely soluble in chloroform, soluble in water and in glacial acetic acid, slightly soluble in ethanol and in acetonitrile and practically insoluble in ethyl acetate and in n-hexane. Donepezil AN 5 mg tablets are white to off-white, round, bevelled edged, biconvex, film coated tablet with inscription "5" on one side and plain on other side. Donepezil AN 10 mg tablets are yellow, round, biconvex, film coated tablet with inscription "10" on one side and plain on other side. Donepezil AN tablets contains the following excipients: lactose, maize starch, microcrystalline cellulose, hydroxypropylcellulose, magnesium stearate, Opadry complete film coating system OY -38951 WHITE [PI No.: 106399] (for 5 mg strength) and Opadry complete film coating system 03B32654 YELLOW [PI No.: 106398] (for 10 mg strength). PHARMACOLOGY _Donepezil AN tablets Product Information _ _ _ _Amneal Pharma Australia Pty Ltd _ Donepezil AN PI v3.0 Page 2 It It has been demonstrated that Alzheimer's disease is associated with a relative decrease in the activity of the cholinergic system in the cerebral cortex and other areas of the brain. Studies suggest that donepezil hydrochloride exerts its therapeutic effect by enhancing cholinergic function in the central nervous system. This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of acetylcholinesterase. PHARMACODYNAMICS Donepezil hydrochloride Perskaitykite visą dokumentą