CEFTAZIDIME- ceftazidime injection, powder, for solution

Šalis: Jungtinės Valstijos

kalba: anglų

Šaltinis: NLM (National Library of Medicine)

Veiklioji medžiaga:

CEFTAZIDIME (UNII: 9M416Z9QNR) (CEFTAZIDIME ANHYDROUS - UNII:DZR1ENT301)

Prieinama:

Sandoz Inc

Vartojimo būdas:

INTRAVENOUS

Recepto tipas:

PRESCRIPTION DRUG

Terapinės indikacijos:

Ceftazidime for injection, USP is indicated for the treatment of patients with infections caused by susceptible strains of the designated organisms in the following diseases: Ceftazidime for injection, USP may be used alone in cases of confirmed or suspected sepsis. Ceftazidime has been used successfully in clinical trials as empiric therapy in cases where various concomitant therapies with other antibiotics have been used. Ceftazidime for injection, USP may also be used concomitantly with other antibiotics, such as aminoglycosides, vancomycin, and clindamycin; in severe and life-threatening infections; and in the immunocompromised patient. When such concomitant treatment is appropriate, prescribing information in the labeling for the other antibiotics should be followed. The dose depends on the severity of the infection and the patient’s condition. To reduce the development of drug-resistant bacteria and maintain the effectiveness of ceftazidime for injection, USP and other antibacterial drugs, ceftazidime f

Produkto santrauka:

Ceftazidime for injection, USP in the dry state should be stored at 20° to 25°C (68° to 77°F) [See USP controlled room temperature] and protected from light. Ceftazidime for injection, USP is a white to cream-colored crystalline powder supplied in Pharmacy Bulk Package Bottles as follows: NDC 0781-3179-86 6 g* Pharmacy Bulk Package Bottle (Tray of 6) *Equivalent to anhydrous ceftazidime.

Autorizacija statusas:

Abbreviated New Drug Application

Prekės savybės

CEFTAZIDIME- CEFTAZIDIME INJECTION, POWDER, FOR SOLUTION
SANDOZ INC
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CEFTAZIDIME FOR INJECTION, USP
PHARMACY BULK PACKAGE - NOT FOR DIRECT INFUSION
FOR INTRAVENOUS USE
To reduce the development of drug-resistant bacteria and maintain the
effectiveness of ceftazidime for
injection and other antibacterial drugs, ceftazidime for injection
should be used only to treat or prevent
infections that are proven or strongly suspected to be caused by
bacteria.
DESCRIPTION
Ceftazidime is a semisynthetic, broad-spectrum, beta-lactam antibiotic
for parenteral administration. It is
the pentahydrate of pyridinium,
1-[[7-[[(2-amino-4-thiazolyl)[(1-carboxy-1-
methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,
hydroxide, inner salt, [6R-[6α,7β(Z)]]. It has the following
structural formula:
The molecular formula is C
H N O S , representing a molecular weight of 636.6.
Ceftazidime for injection, USP is a sterile, dry-powdered mixture of
ceftazidime pentahydrate and
sodium carbonate. The sodium carbonate at a concentration of 118 mg/g
of ceftazidime activity has been
admixed to facilitate dissolution. The total sodium content of the
mixture is approximately 54 mg (2.3
mEq)/g of ceftazidime activity.
Ceftazidime for injection, USP is a white to cream-colored crystalline
powder. Solutions of
ceftazidime for injection, USP range in color from light yellow to
amber, depending on the diluent and
volume used. The pH of freshly constituted solutions usually ranges
from 5 to 8.
Ceftazidime for injection, USP in sterile crystalline form is supplied
in 6 gram Pharmacy Bulk Package
bottles equivalent to 6 grams of anhydrous ceftazidime.
The Pharmacy Bulk Package bottle contains 708 mg of sodium carbonate.
The sodium content is
approximately 54 mg (2.3 mEq) per gram of ceftazidime.
The 6 g Pharmacy Bulk Package bottle is a container of sterile
preparation for parenteral use that
contains many single doses. The contents are intended for use in a
pharmacy admixture program and are
restricte