Šalis: Armėnija
kalba: anglų
Šaltinis: Դեղերի և բժշկական տեխնոլոգիաների փորձագիտական կենտրոնի գործունեության Հայաստանի Հանրապետությունում
povidone-iodine
Arpimed LLC
povidone-iodine
100mg/g
cream
OTC
1 SUMMARY PRODUCT CHARACTERISTIC (SPC) BETAIODINE 10% CREAM FOR TOPICAL USE TRADE NAME – Betaiodine INTERNATIONAL NON-PROPERTY NAME – Povidone Iodine COMPOSITION Each gram of Betaiodine, 10% cream contains: _ACTIVE INGREDIENT: _povidone iodine – 100 mg; _INACTIVE INGREDIENTS:_ ceteareth 12, ceteareth 20, cetostearyl alcohol, paraffin liquid, glycerin, sodium dibasic phosphate, citric acid, water purified. CHEMICAL NAME AND CAS NUMBER 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine; 25655-41-8. PHARMACOLOGICAL GROUP AND ATC CODE Antiseptic; ATC code - D08AG02, G01AX11. PHARMACOLOGICAL ACTION Betaiodine - povidone-iodine - is an iodophore that is used as a disinfectant and antiseptic mainly for the treatment of contaminated wounds and pre-operative preparation of the skin and mucous membranes as well as for the disinfection of equipment. Iodophores are loose complexes of iodine and carrier polymers. Solutions of povidone-iodine gradually release iodine to exert an effect against bacteria, fungi, viruses, protozoa, cysts, and spores. Bactericidal effect usually develops within 15 – 60 s. Povidone-iodine is thus less potent than preparations containing free iodine but it is less toxic. Betaiodine 10 % cream contents almost 0.1 % free iodine. PHARMACOKINETICS After contact with skin and mucous complex of polyvinylpyrrolidone iodine 30% is converted into iodide, and the rest - in the bactericidal activity of iodine. Iodine is slightly absorbed when applied to the skin. When taken by mouth, iodine preparations (which are converted to iodide) are transported to, and concentrated in, the thyroid gland. Iodides not taken up by the thyroid are excreted mainly in the urine, with smaller amounts appearing in the faeces, saliva, and sweat. They cross the placenta and are distributed into breast milk. _ _ USES As an antiseptic for infected lesions of a skin. _ _ _ _DOSAGE Cream for topical use. Clean the affected area. Apply a small amount of this product on clean and dry skin surface 1 to 2 times daily. Du Perskaitykite visą dokumentą