국가: 말레이시아
언어: 영어
출처: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
VALSARTAN
Generic Health Sdn. Bhd.
VALSARTAN
28tablet Tablets
Jubilant Generics Limited
_Consumer Medication Information Leaflet (RiMUP) _ VASTANLUPI FILM COATED TABLETS valsartan (80mg and 160mg) 1 WHAT IS IN THIS LEAFLET 1. What Vastanlupi is used for 2. How Vastanlupi works 3. Before you use Vastanlupi 4. How to use Vastanlupi 5. While you are using it 6. Side Effects 7. Storage and Disposal of Vastanlupi 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of Revision 1. WHAT VASTANLUPI IS USED FOR Vastanlupi can be used to treat high blood pressure. High blood pressure increases the workload on the heart and arteries. If not treated it can damage the blood vessels of the brain, heart, and kidneys, and may result in a stroke, heart failure, or kidney failure. High blood pressure increases the risk of heart attacks. Lowering your blood pressure to normal reduces the risk of developing these disorders. Vastanlupi is used to treat adult heart failure patients. Heart failure is associated with shortness of breath, and swelling of the feet and legs due to fluid build-up. Heart failure means that the heart muscle cannot pump blood strongly enough to supply all the blood needed throughout the body. Vastanlupi can also be used to treat adults after a heart attack (myocardial infarction) to improve survival and reduce further heart problems. 2. HOW VASTANLUPI WORKS Vastanlupi belongs to a class of medicines known as angiotensin II receptor antagonist, which help to control high blood pressure. Angiotensin II is a substance in the body that causes vessels to tighten, thus causing your blood pressure to increase. Vastanlupi works by blocking the effect of angiotensin II. As a result, blood vessels relax and blood pressure is lowered 3. BEFORE YOU USE VASTANLUPI _ _ _WHEN YOU MUST NOT USE IT _ • if you are ALLERGIC (hypersensitive) to valsartan or any of the other ingredients of Vastanlupi. • if you are pregnant or planning to be pregnant. _ _ _BEFORE YOU USE IT _ Follow all instructions given to you by your doctor carefully, even if they differ from the information contained 전체 문서 읽기
For the use of a registered medical practitioner or a hospital or a laboratory only VASTANLUPI FILM COATED TABLETS 80 MG & 160 MG PRODUCT NAME: Vastanlupi Film Coated Tablets 80 mg Vastanlupi Film Coated Tablets 160 mg NAME AND STRENGTH OF ACTIVE INGREDIENT: Each film-coated tablet contains: Valsartan Ph. Eur…..80 mg Valsartan Ph. Eur…..160 mg PRODUCT DESCRIPTION: VASTANLUPI FILM COATED TABLETS 80 MG Peach coloured, round, biconvex, film coated tablets, scored on one side and debossed with ‘80’ on scored side and ‘J’ on the other. VASTANLUPI FILM COATED TABLETS 160 MG Yellow coloured, oval shaped, biconvex, film coated tablets, scored on one side and debossed with ‘160’ on scored side and ‘J’ on the other. PHARMACODYNAMICS / PHARMACOKINETICS: Angiotensin II antagonist. The active hormone of the renin-angiotensin-aldosterone system (RAAS) is angiotensin II, which is formed from angiotensin I through ACE. Angiotensin II binds to specific receptors located in the cell membranes of various tissues. It has a wide variety of physiological effects, including in particular both direct and indirect involvement in the regulation of blood pressure. As a potent vasoconstrictor, angiotensin II exerts a direct pressor response. In addition, it promotes sodium retention and stimulation of aldosterone secretion. Valsartan is an orally active, potent and specific angiotensin II (Ang II) receptor antagonist. It acts selectively on the AT1 receptor subtype, which is responsible for the known actions of angiotensin II. The increased plasma levels of Ang II following AT1 receptor blockade with valsartan may stimulate the unblocked AT2 receptor, which appears to counterbalance the effect of the AT1 receptor. Valsartan does not exhibit any partial agonist activity at the AT1 receptor and has much (about 20,000 fold) greater affinity for the AT1 receptor than for the AT2 receptor. Valsartan does not inhibit ACE, also known as kininase II, which converts Ang I to Ang II and degrades bradykinin. Since there is no effec 전체 문서 읽기