SYNOVEX PLUS- trenbolone acetate and estradiol benzoate implant

국가: 미국

언어: 영어

출처: NLM (National Library of Medicine)

유효 성분:

TRENBOLONE ACETATE (UNII: RUD5Y4SV0S) (TRENBOLONE - UNII:P53R4420TR), ESTRADIOL BENZOATE (UNII: 1S4CJB5ZGN) (ESTRADIOL - UNII:4TI98Z838E)

제공처:

Zoetis Inc.

관리 경로:

SUBCUTANEOUS

처방전 유형:

OTC

치료 징후:

Not for use in humans. Keep out of reach of children. • For increased rate of weight gain and improved feed efficiency in growing beef steers fed in confinement for slaughter and for increased rate of weight gain in growing beef heifers fed in confinement for slaughter. SYNOVEX Plus® is not more effective than SYNOVEX Choice® (100 mg trenbolone acetate and 14 mg estradiol benzoate per implant) for increased rate of weight gain in growing beef steers fed in confinement for slaughter. • For increased rate of weight gain for up to 200 days in growing beef steers and heifers fed in confinement for slaughter in a reimplantation program where SYNOVEX Choice® is the first implant and a SYNOVEX Plus® implant is administered 60 to 120 days later. • Other than as described on the labeling, this implant is not approved for repeated implantation (reimplantation) with any other cattle ear implant in growing beef steers and heifers fed in confinement for slaughter as safety and effectiveness have not been evaluated.

승인 상태:

New Animal Drug Application

제품 특성 요약

SYNOVEX PLUS- TRENBOLONE ACETATE AND ESTRADIOL BENZOATE IMPLANT
ZOETIS INC.
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SYNOVEX PLUS®
SUBCUTANEOUS IMPLANTS FOR GROWING BEEF STEERS AND HEIFERS FED IN
CONFINEMENT FOR SLAUGHTER
SYNOVEX PLUS®
(trenbolone acetate and estradiol benzoate implants)
200 mg trenbolone acetate and 28 mg estradiol benzoate
SYNOVEX Plus® (trenbolone acetate and estradiol benzoate implants) is
a growth
promoting implant containing 200 mg of trenbolone acetate and 28 mg of
estradiol
benzoate per implant. Each implant consists of 8 pellets. Ten implants
are provided in
each cartridge.
NOTE: Administration of a single SYNOVEX Plus® implant or its use in
a reimplantation
program with a SYNOVEX Choice® implant may result in decreased
marbling scores
when compared to non-implanted steers and heifers.
DOSAGE
One implant (eight pellets), containing 200 mg of trenbolone acetate
and 28 mg of
estradiol benzoate, is administered to each steer or heifer by
subcutaneous implantation
in the middle one‑third of the ear.
The ten-dose cartridge of Synovex Plus is designed to be used
exclusively with a
Synovex implanting device.
WITHDRAWAL PERIODS AND RESIDUE WARNINGS
No withdrawal period is required when used according to labeling.
Do not use in beef calves less than 2 months of age, dairy calves, and
veal calves. A
withdrawal period has not been established for this product in
pre-ruminating calves.
Do not use in dairy cows or in animals intended for subsequent
breeding. Use in these
cattle may cause drug residues in milk and/or in calves born to these
cows. Implant
pellets subcutaneously in ear only. Any other location is a violation
of Federal law. Do not
attempt salvage of implanted site for human or animal food.
USER SAFETY WARNINGS
Not for use in humans. Keep out of reach of children.
ANIMAL SAFETY WARNINGS
Bulling has occasionally been reported in implanted steers and
heifers. Vaginal and rectal
prolapse, udder development, ventral edema and elevated tailheads have
occasionally
been reported in heifers administered SYNOVEX Plus®