국가: 말레이시아
언어: 영어
출처: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
RISPERIDONE
UNIMED SDN BHD
RISPERIDONE
30Tablet Tablets
M/s. Aurobindo Pharma Limited,
RESICALM RISPERIDONE TABLET 1MG, 2MG AND 3MG RISPERIDONE ORAL SOLUTION 1MG/ML DESCRIPTION AND COMPOSITIONS: _RISPERIDONE TABLETS 1MG _ White coloured film coated, biconvex, caplets, debossed on one side with “A” and on the other side with “51”. Score line between “5’ and “1”. Each film coated tablet contains Risperidone 1mg. _RISPERIDONE TABLETS 2MG _ Light orange coloured film coated, biconvex, caplets, debossed on one side with “A” and on the other side with “52”. Score line between “5’ and “2”. Each film coated tablet contains Risperidone 2mg. _RISPERIDONE TABLETS 3MG _ Yellow coloured film coated, biconvex, caplets, debossed on one side with “A” and on the other side with “53”. Score line between “5’ and “3”. Each film coated tablet contains Risperidone 3mg. _RESICALM 1 (RISPERIDONE ORAL SOLUTION 1 MG/ ML) _ A clear, colourless liquid Each ml of Risperidone equivalent to Risperidone 1 mg. PROPERTIES _PHARMACODYNAMIC PROPERTIES _ Risperidone is a selective monoaminergic antagonist with unique properties. It has a high affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors. Risperidone binds also to alpha1 adrenergic receptors, and with lower affinity to H1 histaminergic and alpha2 adrenergic receptors. Risperidone is a potent D2 antagonist, which is considered to improve the positive symptoms of schizophrenia, it causes less depression of motor activity and induction of catalepsy than classical neuroleptics. Balanced central serotonin and dopamine antagonism may reduce extrapyramidal side effects liability and extend the therapeutic activity to the negative and effective symptoms of schizophrenia. _PHARMACOKINETIC PROPERTIES _ Risperidone is completely absorbed after oral administration, reaching peak plasma concentrations within 1 to 2 hours. The absorption is not affected by food and thus risperidone can give with or without meals._ _ Risperidone is metabolized by cytochrome P-450 llD6 to 9-hydroxy-risperidone which has a similar pharmacological activi 전체 문서 읽기