Pharmasin® 250 mgg Premix for Medicated Feeding Stuff

국가: 말레이시아

언어: 영어

출처: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

유효 성분:

TYLOSIN PHOSPHATE

제공처:

PAHANG PHARMACY SDN. BHD.

INN (국제 이름):

TYLOSIN PHOSPHATE

패키지 단위:

20 kg; 1 kg

Manufactured by:

Biovet Joint Stock Company

제품 특성 요약

LfB3097v3-Phar250mp-MAL1118
®
PHARMASIN 250 MG/G
PREMIX FOR MEDICATED FEEDING STUFF
Keep out of reach of children.
STATEMENT OF ACTIVE
SUBSTANCE:
Tylosin (as tylosin phosphate):
250 mg per g. (equivalent to
250 000 IU)
PRODUCT DESCRIPTION:
Pharmasin ® 250 mg/g Premix for
Medicated Feeding Stuff for Pigs,
Broilers and Pullets represents off-
white to beige granules.
PHARMACODYNAMICS:
Tylosin is a macrolide antibiotic
produced by a strain of
_Streptomyces_ _fradiae_. It exerts its
antimicrobial effect by inhibiting
protein synthesis of susceptible
micro-organisms.
The tylosin spectrum of activity
includes Gram-positive bacteria,
some Gram – negative strains such
as _Pasteurella_, and _Mycoplasma_
_spp_. at concentrations of 16 µg/ml or
less.
PHARMACOKINETICS:
In most species peak plasma
concentrations have been attained 1
to 2 hours after administration of
tylosin. Compared to plasma levels
clearly higher tissue concentrations
have been observed. Tylosin was
extensively metabolized. Most of the
residues are excreted in faeces
predominantly consisting of tylosin A,
tylosin factor D and
dihydrodesmycosin.
INDICATIONS FOR USE:
Pigs: Treatment and prevention of
Porcine Intestinal Adenomatosis
(Ileitis) associated with _Lawsonia_
_intracellularis_ when the disease has
been diagnosed at the group or herd
level.
Broilers and pullets: Treatment and
prevention of respiratory infections
caused by _Mycoplasma_
_gallisepticum_ and _Mycoplasma_
_synoviae_, when the disease has
been diagnosed in the flock.
Treatment and prevention of necrotic
enteritis caused by _Clostridium _
_perfringens_, when the disease has
been diagnosed in the flock.
RECOMMENDED DOSAGE AND
MODE OF ADMINISTRATION:
Administration through the feed: for
the preparation of a medicated feed
containing 40-1100 gram tylosine per
ton of feed, the required amount of
product should be homogenously
mixed with a suitable carrier into a
feed premixture so that at least 5 kg
of this premixture can be added to
the feed in order to obtain a
medicated feed with the