국가: 영국
언어: 영어
출처: MHRA (Medicines & Healthcare Products Regulatory Agency)
Losartan potassium; Hydrochlorothiazide
Milpharm Ltd
C09DA01
Losartan potassium; Hydrochlorothiazide
100mg ; 25mg
Oral tablet
Oral
No Controlled Drug Status
Valid as a prescribable product
BNF: 02050502; GTIN: 8901175013289
• if you need to have an anaesthetic (even at the dentist) or before surgery, or if you are going to have tests to check your parathyroid function, you must tell the doctor or medical staff that you are taking Losartan potassium and Hydrochlorothiazide tablets. • if you suffer from primary hyperaldosteronism (a syndrome associated with increased secretion of the hormone aldoesterone by the adrenal gland, caused by an abnormality within the gland). • if you are taking any of the following medicines used to treat high blood pressure. - an ACE-inhibitor (for example enalapril, lisinopril, ramipril), in particular if you have diabetes-related kidney problems. - aliskiren. Your doctor may check your kidney function, blood pressure, and the amount of electrolytes (e.g. potassium) in your blood at regular intervals. See also information under the heading “Do not take Losartan potassium /Hydrochlorothiazide”. CHILDREN AND ADOLESCENTS There is no experience with the use of Losartan potassium/Hydrochlorothiazide in children. Therefore, Losartan potassium/Hydrochlorothiazide should not be given to children. OTHER MEDICINES AND LOSARTAN POTASSIUM / HYDROCHLOROTHIAZIDE Tell your doctor or pharmacist if you are taking have recently taken or might take any other medicines. Diuretic agents such as the hydrochlorothiazide contained in Losartan potassium/Hydrochlorothiazide may interact with other medicines. Preparations containing lithium should not be taken with Losartan potassium/Hydrochlorothiazide without close supervision by your doctor. Special precautionary measures (e.g. blood tests) may be appropriate if you take potassium supplements, potassium-containing salt substitutes or potassium-sparing medicines, other diuretics (“water tablets”), some laxatives, medicines for the treatment of gout, medicines to control heart rhythm or for diabetes (oral agents or insulins). It is also important for your doctor to know if you are taking: • other medicines to reduce your blood pressure • steroids • medicines to 전체 문서 읽기
OBJECT 1 LOSARTAN POTASSIUM/HYDROCHLOROTHIAZIDE 100 MG/25 MG FILM-COATED TABLETS Summary of Product Characteristics Updated 04-Jun-2018 | Aurobindo Pharma - Milpharm Ltd. 1. Name of the medicinal product Losartan potassium/Hydrochlorothiazide 100 mg/25 mg film-coated tablets 2. Qualitative and quantitative composition Each tablet contains 100 mg of losartan potassium and 25 mg of hydrochlorothiazide (HCTZ) as the active ingredients. _Excipient _with known effect Each tablet contains 222 mg lactose monohydrate. For the full list of excipients, see section 6.1. 3. Pharmaceutical form Film coated tablet Yellow coloured, oval shaped, beveled edge, biconvex film-coated tablets debossed with 'E' on one side and '49' on the other side. 4. Clinical particulars 4.1 Therapeutic indications Losartan potassium/Hydrochlorothiazide is indicated for the treatment of essential hypertension in patients whose blood pressure is not adequately controlled on losartan or hydrochlorothiazide alone. 4.2 Posology and method of administration Hypertension Losartan potassium and Hydrochlorothiazide is not for use as initial therapy, but in patients whose blood pressure is not adequately controlled by losartan potassium or hydrochlorothiazide alone. Dose titration with the individual components (losartan and hydrochlorothiazide) is recommended. When clinically appropriate direct change from monotherapy to the fixed combination may be considered in patients whose blood pressure is not adequately controlled. (See Sections 4.3, 4.4, 4.5 and 5.1). The usual maintenance dose of Losartan potassium/Hydrochlorothiazide is one tablet of Losartan potassium/Hydrochlorothiazide 50 mg/12.5 mg (losartan 50 mg/HCTZ 12.5 mg) once daily. For patients who do not respond adequately to Losartan potassium/Hydrochlorothiazide 50 mg/12.5 mg, the dosage may be increased to one tablet of Losartan potassium/Hydrochlorothiazide 100 mg/25 mg (losartan 100 mg/ HCTZ 25 mg) once daily. The maximum dose is one tablet of Losartan potassium/Hydrochlorothiazide 100 mg/25 mg 전체 문서 읽기