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LINCOCIN
®
_lincomycin hydrochloride_
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET
Please read this leaflet carefully
before you start using LINCOCIN
injection. This leaflet answers some
common questions about LINCOCIN
injection. It does not contain all the
available information. It does not
take the place of talking to your
doctor or pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using LINCOCIN
against the benefits it is expected to
have for you. Use LINCOCIN as
instructed and follow the advice
given in this leaflet.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
Keep this leaflet with your medicine.
You may need to read it again.
WHAT LINCOCIN IS
USED FOR
LINCOCIN is an antibiotic used to
treat serious infections in different
parts of the body caused by certain
bacteria. LINCOCIN works by
killing or stopping the growth of
bacteria causing your infection.
The specific infections for which
LINCOCIN is used include: ear,
throat and lung infections; skin
infections; bone and joint infections;
and infections of the blood.
LINCOCIN will not work against
viral infections such as colds or flu.
Your doctor may have prescribed
LINCOCIN for another reason.
Ask your doctor if you have any
questions about why LINCOCIN has
been prescribed for you.
This medicine is available only with
a doctor's prescription.
LINCOCIN is not addictive.
BEFORE YOU USE
LINCOCIN
Some information is provided below.
However, always talk to your doctor
if you have concerns or questions
about your treatment.
_WHEN YOU MUST NOT USE_
_LINCOCIN_
DO NOT USE LINCOCIN IF:
1. YOU HAVE AN ALLERGY TO:
•
CLINDAMYCIN OR LINCOMYCIN
•
ANY OF THE OTHER INGREDIENTS
LISTED AT THE END OF THIS LEAFLET
(see 'Product Description')
Symptoms of an allergic reaction
may include skin rash, itching or
difficulty in breathing, wheezing
or coughing (anaphylactic
reactions). If you are not sure if
you have or have had an allergic
reaction to LINCOCIN, check
with
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Version: pfplinci10513
Supersedes: pfplinci10413
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PRODUCT INFORMATION
LINCOCIN
®
LINCOMYCIN INJECTION
NAME OF THE MEDICINE
Non-proprietary name: lincomycin hydrochloride
Chemical Name: Lincomycin hydrochloride consists mainly of the monohydrate of methyl
6,8-dideoxy-6-[(_2S,4R_)-1-methyl-4-propylpyrrolidine-2-carboxamido]-1-thio-
D
-erythro-
-
D
-
galacto-octopyranoside hydrochloride.
CAS Number: 7179-49-9
The structure of lincomycin hydrochloride is:
DESCRIPTION
LINCOCIN (lincomycin hydrochloride) is the monohydrated salt of lincomycin, a substance
produced by the growth of a member of the lincolnensis group of _Streptomyces lincolnensis _
_(fam. Streptomycetaceae)_. It is a white, or practically white, crystalline powder and is
odourless or has a faint odour. Its solutions are acid and are dextrorotatory. LINCOCIN is
freely soluble in water, soluble in dimethylformamide and
very slightly soluble in acetone.
LINCOCIN Injection is a clear, colourless or almost colourless solution, practically free from
particles.
PHARMACOLOGY
MICROBIOLOGY
_In vitro_ studies indicate that the following organisms are usually sensitive to concentrations
achieved normally in the serum following recommended doses: _Staphylococcus aureus, _
_Staphylococcus epidermidis_, beta-haemolytic Streptococcus, _Streptococcus viridans, _
Version: pfplinci10513
Supersedes: pfplinci10413
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_Streptococcus pneumoniae, Clostridium tetani, Clostridium perfringens, Corynebacterium _
_diphtheriae._
NOTE:
The drug is not active against most strains of _Enterococcus faecalis_, nor against _Neisseria _
_gonor
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