CYTOMEL- liothyronine sodium tablet

국가: 미국

언어: 영어

출처: NLM (National Library of Medicine)

유효 성분:

LIOTHYRONINE SODIUM (UNII: GCA9VV7D2N) (LIOTHYRONINE - UNII:06LU7C9H1V)

제공처:

A-S Medication Solutions

INN (International Name):

LIOTHYRONINE SODIUM

구성:

LIOTHYRONINE 5 ug

관리 경로:

ORAL

처방전 유형:

PRESCRIPTION DRUG

치료 징후:

Thyroid hormone drugs are indicated: As replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis. This category includes cretinism, myxedema and ordinary hypothyroidism in patients of any age (pediatric patients, adults, the elderly), or state (including pregnancy); primary hypothyroidism resulting from functional deficiency, primary atrophy, partial or total absence of thyroid gland, or the effects of surgery, radiation, or drugs, with or without the presence of goiter; and secondary (pituitary) or tertiary (hypothalamic) hypothyroidism (see Warnings ). As pituitary thyroid-stimulating hormone (TSH) suppressants, in the treatment or prevention of various types of euthyroid goiters, including thyroid nodules, subacute or chronic lymphocytic thyroiditis (Hashimoto's) and multinodular goiter. As diagnostic agents in suppression tests to differentiate suspected mild hyperthyroidism or thyroid gland auton

제품 요약:

Product: 50090-0413 NDC: 50090-0413-5 120 TABLET in a BOTTLE

승인 상태:

New Drug Application

제품 특성 요약

CYTOMEL- LIOTHYRONINE SODIUM TABLET
A-S MEDICATION SOLUTIONS
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CYTOMEL
BRAND OF LIOTHYRONINE SODIUM TABLETS
CYTOMEL TABLET
DES CRIPTION
Thyroid hormone drugs are natural or synthetic preparations containing
tetraiodothyronine (T ,
levothyroxine) sodium or triiodothyronine (T , liothyronine) sodium or
both. T and T are produced in
the human thyroid gland by the iodination and coupling of the amino
acid tyrosine. T contains four
iodine atoms and is formed by the coupling of two molecules of
diiodotyrosine (DIT). T contains three
atoms of iodine and is formed by the coupling of one molecule of DIT
with one molecule of
monoiodotyrosine (MIT). Both hormones are stored in the thyroid
colloid as thyroglobulin.
Thyroid hormone preparations belong to two categories: (1) natural
hormonal preparations derived from
animal thyroid, and (2) synthetic preparations. Natural preparations
include desiccated thyroid and
thyroglobulin. Desiccated thyroid is derived from domesticated animals
that are used for food by man
(either beef or hog thyroid), and thyroglobulin is derived from
thyroid glands of the hog. The United
States Pharmacopeia (USP) has standardized the total iodine content of
natural preparations. Thyroid
USP contains not less than (NLT) 0.17 percent and not more than (NMT)
0.23 percent iodine, and
thyroglobulin contains not less than (NLT) 0.7 percent of organically
bound iodine. Iodine content is
only an indirect indicator of true hormonal biologic activity.
Cytomel (liothyronine sodium) Tablets contain liothyronine
(L-triiodothyronine or LT ), a synthetic
form of a natural thyroid hormone, and is available as the sodium
salt.
The structural and empirical formulas and molecular weight of
liothyronine sodium are given below.
Liothyronine Sodium
L-Tyrosine, _O_-(4-hydroxy-3-iodophenyl)-3,5-diiodo-, monosodium salt
Twenty-five mcg of liothyronine is equivalent to approximately 1 grain
of desiccated thyroid or
thyroglobulin and 0.1 mg of L-thyroxine.
Each round, white to off-white Cytomel (liothyronine sodium) t