국가: 말레이시아
언어: 영어
출처: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
CALCIUM GLUCONATE; MAGNESIUM HYPOPHOSPHITE
Rhone Ma Malaysia Sdn Bhd
CALCIUM GLUCONATE; MAGNESIUM HYPOPHOSPHITE
500.00 mcg/mL
Dopharma France
COFACALCIUM SOLUTION FOR INJECTION COMPOSITION/ML: Calcium gluconate 280 mg Magnesium hypophosphite 90 mg PRODUCT DESCRIPTION: A clear colourless solution, odourless, acid taste. PHARMACODYNAMICS: The concentrated solute of calcium and magnesium hypophosphite supplies the body in salts of calcium, magnesium and phosphorous directly metabolisable. Their parenteral administration allows to increase quickly the plasma concentration of these ions for the treatment of hypocalcaemia associated with hypomagnesia and/or hypophosphatemia. PHARMACOKINETICS: After parenteral administration, calcium, magnesium and phosphorous are quickly distributed in the body. The binding rate to plasma proteins is about 50% for calcium and from 30 to 50% for magnesium. Calcium is mainly eliminated in faeces and magnesium by urinary route. INDICATION: Cattle, sheep, goats, horses, pigs, dogs and cats: Preventive and curative treatment of hypocalcemia and/or hypomagnesia and/or hypophosphatemia such as milk fever, parturient paresis, grass tetany, eclampsia. ROUTES OF ADMINISTRATION: Intramuscular, subcutaneous or slow intravenous routes. DOSAGE: 12.5 to 25 mg of calcium and 26.5 to 52.9 mg of magnesium hypophosphite per kg of body weight per administration, equivalent to 0.5 ml to 1 ml per kg of body weight by slow intravenous, intramuscular or subcutaneous injection. The administration may be repeated every 12 hours for 1 to 2 consecutive days if necessary. CONTRAINDICATIONS: Do not use in animals having cardiac disorders. WARNINGS AND PRECAUTIONS: SPECIAL WARNINGS FOR EACH TARGET SPECIES None. SPECIAL PRECAUTIONS FOR USE IN ANIMALS The solution must be warmed to body temperature before administration. Administer the product by slow intravenous administration, as a infusion, and stop immediately if any adverse reactions appears. When the product is administered by intramuscular or sub-cutaneous route, divide the total dose into multiple injection sites in order to minimize local reactions. The use or reuse of this product may be subject t 전체 문서 읽기