환자 정보 전단
CHEMMART MELOXICAM
TABLETS
_Contains the active ingredient, meloxicam_
CONSUMER MEDICINE INFORMATION
_FOR A COPY OF A LARGE PRINT LEAFLET, PH: 1800 195 055_
WHAT IS IN THIS LEAFLET
READ THIS LEAFLET CAREFULLY BEFORE
TAKING YOUR MEDICINE
This leaflet answers some common
questions about meloxicam. It does
not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
The information in this leaflet was
last updated on the date listed on the
last page. More recent information on
this medicine may be available.
ASK YOUR DOCTOR OR PHARMACIST:
•
if there is anything you do not
understand in this leaflet,
•
if you are worried about taking
your medicine, or
•
to obtain the most up-to-date
information
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using this medicine
against the benefits they expect it
will have for you.
Pharmaceutical companies cannot
give you medical advice or an
individual diagnosis.
Keep this leaflet with your medicine.
You may want to read it again.
WHAT THIS MEDICINE IS
USED FOR
The name of your medicine is
Chemmart Meloxicam. It contains
the active ingredient meloxicam.
It is used to treat the symptoms of:
•
osteoarthritis
•
rheumatoid arthritis.
Both diseases mainly affect the
joints, causing pain and swelling.
Although meloxicam can relieve
symptoms such as pain and
inflammation, it will not cure your
condition.
Ask your doctor if you have any
questions about why this medicine
has been prescribed for you. Your
doctor may have prescribed this
medicine for another reason.
Ask your doctor if you have any
questions about why this medicine
has been prescribed for you. Your
doctor may have prescribed this
medicine for another reason.
This medicine is available only with
a doctor's prescription.
_HOW IT WORKS_
Meloxicam belongs to a family of
medicines called Non-Steroidal Anti-
inflammatory Drugs (NSAIDs).
These medicines work by relieving
pain and inflammation.
This medicine is available only with
a doctor's pre
전체 문서 읽기
제품 특성 요약
Product Information – Australia
Chemmart Meloxicam Tablets
Page 1
CHEMMART MELOXICAM TABLETS
NAME OF THE MEDICINE
Meloxicam.
Chemical Name:
4-Hydroxy-2-methyl-_N_-(5-methyl-1,3-thiazol-2-yl)-2_H_-1,2-benzothiazine-3-
carboxamide-1,1-dioxide
Structural Formula:
Molecular Formula:
C
14
H
13
N
3
O
4
S
2
Molecular Weight: 351.4
CAS Registry Number:
71125-38-7
DESCRIPTION
Meloxicam is a pale yellow powder, practically insoluble in water,
slightly soluble in acetone, soluble in
dimethylformamide, very slightly soluble in ethanol (96%) and in
methanol.
Each tablet contains meloxicam as the active ingredient. In addition,
each tablet contains the following
inactive ingredients: microcrystalline cellulose, croscarmellose
sodium, lactose, magnesium stearate,
colloidal anhydrous silica, sodium bicarbonate.
PHARMACOLOGY
PHARMACOLOGICAL ACTIONS
Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) of the
enolic acid class, which has
shown anti-inflammatory, analgesic and antipyretic properties in
animals. Meloxicam showed anti-
inflammatory activity in all standard models of inflammation. A common
mechanism for the above
effects may exist in the ability of meloxicam to inhibit the
biosynthesis of prostaglandins, known
mediators of inflammation, by inhibition of cyclooxygenase (COX).
Comparison of the ulcerogenic dose and the anti-inflammatory effective
dose in rat adjuvant arthritis
model confirmed a greater therapeutic margin in animals over other
NSAIDs (piroxicam, diclofenac,
naproxen,
flurbiprofen).
In
rats,
meloxicam
showed
greater
inhibitory
effect
on
prostaglandin
biosynthesis at the site of inflammation than in the gastric mucosa or
the kidney.
Selective inhibition of the cyclooxygenase-2 (COX-2) isoenzyme,
relative to COX-1, by meloxicam has
been demonstrated _in vitro_ on various cell systems: guinea pig
macrophages, bovine aortic endothelial
cells (for testing of COX-1 activity), mouse macrophages (for testing
for COX-2 activity), and human
recombinant enzymes expressed in cos cells and in human whole blood
전체 문서 읽기
환자 정보 전단 