국가: 남아프리카
언어: 영어
출처: South African Health Products Regulatory Authority (SAHPRA)
Schering
ADVANTAN SCHEDULING STATUS S4 PROPRIETARY NAME (and dosage form): ADVANTAN CREAM, OINTMENT, FATTY OINTMENT Corticoid skin preparations COMPOSITION 1 g Advantan contains methylprednisolone aceponate (21-acetoxy-11beta-hydroxy-6alpha-methyl-17-propionyloxy- 1,4-pregnadiene-3,20-dione) 1 mg. The cream contains benzyl alcohol 1% (w/w) as preservative. PHARMACOLOGICAL CLASSIFICATION A. 13.4.1 Corticosteroids without anti-infective agents. PHARMACOLOGICAL ACTION After topical application, Advantan has antiinflammatory, antipruritic and vasoconstrictive actions. INDICATIONS Endogenous eczema (atopic dermatitis, neurodermatitis), contact eczema, dyshidrotic and other eczemas. CONTRA-INDICATIONS Tuberculous or syphilitic processes in the area to be treated; virus diseases (eg herpes simplex, vaccinia, chickenpox, shingles). Corticosteroids have been shown to be teratogenic in animals following dermal application. As these agents are absorbed percutaneously, teratogenicity following topical application cannot be excluded. Therefore Advantan should not be used during pregnancy. DOSAGE AND DIRECTIONS FOR USE For external use only. The Advantan formulation appropriate to the skin condition is applied thinly once per day to the diseased areas of skin. In general, the duration of use should not exceed 12 weeks in adults and 4 weeks in children. The respective bases are of major importance to the therapeutic effect of the Advantan formulations. • Advantan cream As a low-fat formulation with a high water content, Advantan cream is particularly suitable for acute and weeping stages of eczema, for very greasy skin and for use on exposed or hairy parts of the body. If the skin dries out excessively under protracted use of Advantan cream, a switch should be made to one of the fattier formulations (Advantan o 전체 문서 읽기