喜克脂膜衣錠40毫克

국가: 대만

언어: 중국어

출처: 衛生福利部食品藥物管理署 (Ministry of Health and Welfare, Food And Drug Administration)

유효 성분:

SIMVASTATIN

제공처:

台灣山德士藥業股份有限公司 臺北市中山區民生東路3段2號8樓 (90003886)

ATC 코드:

C10AA01

약제 형태:

膜衣錠

구성:

SIMVASTATIN (2406002900) MG

패키지 단위:

鋁箔盒裝

수업:

製　劑

처방전 유형:

須由醫師處方使用

Manufactured by:

Sandoz Grup Saglik Urunleri Ilaclari San. ve Tic. A.S. GOSB Ihsan Dede Cad. 900 Sok. TR-41400 Gebze-Kocaeli, Turkey TR

치료 영역:

simvastatin

치료 징후:

高膽固醇血症，高三酸甘油酯血症，降低冠心病高危險群或冠心病患者的心血管事件發生率及冠心病致死率、患有異核質家族性高膽固醇血症的兒童病人。

제품 요약:

有效日期: 2025/12/09; 英文品名: Simvahexal Film-coated Tablets 40mg

승인 날짜:

2005-12-09

환자 정보 전단

Simvahexal
®
(simvastatin)
ᣅ が ⍦ ߗ ⷑ ԵŊ ᮫ ߭ 㓪 Ⓥ
(
Aspergillus terreus
)
ʠᱹⷅᮟ᧎׶ໞ≟വȯ
Simvastatin
ᣅᤀᙙඖʠҙⷁŊםሺരᖛ⤟ᣅҢ Ĩ
-
ᖕᖒ⷇
ࠣ ೣř ᔍ ᣅ Ң ʙ ˩ ⨀ ᧎Ŋ ʈ ᣅ
3-hydroxy-3-methylglutaryl-
coenzyme A, HMG-CoA
ⴒ׆ⷅ₪ʠ༸ӼԵřᔍⷅ₪⪭⪸Аջ
⍦ߗⷑᮝ׶ໞʠᅽቅᔎ㊾ŊҢˇᣅⳌ᪓ᗉહᔎ㊾ȯͩ⎈ಉᶇἄ
ㆴḻ
simvastatin
ଃᯌࠣ࿲׶ઈ
(heterozygous)
૊ᅭඖד㄄૊
ᅭඖ㋧⍦ߗⷑ⠐᯽Ŋᛜ׶ࠣ㋧⠐⋵᯽᯼෧Ң⍦ߗⷑ⳧㋧ʈ܈
᩸˫㇞㇔࿳Ӽᄓኞʃ̈́≛Ŋרሷᄓが̥Ңⅶ⠐ួ⍦ߗⷑ
(total
plasma cholesterol; total-C)
Ȯ̥૓ಙ⋵⛵ᱺ⍦ߗⷑ
(low-density
lipoprotein cholesterol; LDL-C)
Ȯ ɿ ⷇ ᮙ ᗴ ⷁ
(triglycerid
es;
TG)
דᏎ̥૓ಙ⋵⛵ᱺ⍦ߗⷑ
(very-low-density lipoprotein
cholesterol; VLDL-C)
ʏ֗㋧㋧૓ಙ⋵⛵ᱺ⍦ߗⷑ
(HDL-C)
᠝
ಙȯ˫
Simvahexal
®
ᗶ᱗Ŋʷⳕҙ֯רവӷㆴ┮᱗ᄓŊ߈⎏Ҟ
ⳕര֯Ⳮሱ̈́᱗ᄓȯ⃻ྃ↲ᗶ᱗͵רℋྃ⎈ಉ໽ト᱗ᄓȯᯍϟ
ᔋ˫
Simvahexal
®
ᗶ᱗ᆹŊ⠐ʑ⍦ߗⷑُ⠐⋵בߊӷቍᗶ᱗ᆹ
᱿᠝ಙȯ
Simvastatin
ʠ ᙙ ඖ ࠣ ᣅ
HMG-CoA
ⴒ ׆ ⷅ ₪ ʠ ૾ ɺ ඖ ༸
ӼԵřᔍ
HMG-CoA
ⴒ׆ⷅ₪⪭⪸Аջ
HMG-CoA
Ⱨဘໞ
mevalonate
ȯߌ
HMG-CoA
Ⱨဘໞ
mevalonate
ᣅ⍦ߗⷑᮝ׶
ໞⳂലʠᅽቅᔎ㊾ŊߌᔍŊ˫
simvastatin
ᗶ᱗ʏʃሳߌᶶ⋵ⷑ
ㆩ╸Ử≟೧⬚ר⋱ʠᕕඖȯᔍकŊ
HMG-CoA
ʬૌᆞו׿˩⨀
ໞʨⷮⰿⷅ₪
A (acetyl-CoA)
ŊҢרא⎞㋤ҙ⥓घᮝ׶ໞⳂലȯ
߱Ւ᧎ᶇἄʑŊ
simvasta
tin
ᅠםሺരŊଃ⊴⎀ң㋧ಙⴆႹඖŊ
߱ᔍҢ᠝ಙ⳵ᕗ㄄ᐻ᱿⃅ↈᣅ㋧ȯ
Simvastatin
߱ʙ̳ᮢⵒ̤ƞ
⊴⎀⃻ೊᘒʠ㈪᛬
(¿rst pass)
ᄓະ˩⨀രŊらര֯࿢ᗿᅠ⍦ᖢ
ʑȯ߱ːㆩ⠐᚝ʑ
simvastatin
ᙙඖࠣೣ᱿Қ⯿ሀヮ⸇ଅᅠםሺ
Ե⸇᱿
5%
ŊҢʑ
95%
⎞ːㆩ⠐ួ⛵ᱺ᳈⃌׶ȯ
ռ ᓿ ᅗ ࢄ ߸ ⴨ ℋ ˁ ֚ ஌
Simvastatin
એ ᙙ ᪓ ʠ ᶇ ἄ ʑ
(Scandinavian Simvastatin Survival Study: 4S)
Ŋᅠ
4444
̤෧
ሷҴᨊՒ⋸ൔ⎀᯼
(CHD)
Ŋʈⅶ㋤⍦ߗⷑϊ߱