TRIAMCINOLONE ACETONIDE cream

Nazione: Stati Uniti

Lingua: inglese

Fonte: NLM (National Library of Medicine)

Principio attivo:

TRIAMCINOLONE ACETONIDE (UNII: F446C597KA) (TRIAMCINOLONE ACETONIDE - UNII:F446C597KA)

Commercializzato da:

REMEDYREPACK INC.

Via di somministrazione:

TOPICAL

Tipo di ricetta:

PRESCRIPTION DRUG

Indicazioni terapeutiche:

Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.

Dettagli prodotto:

Triamcinolone Acetonide Cream USP, 0.5% is supplied in: NDC: 70518-1094-00 PACKAGING: 15 g in 1 TUBE, TYPE 0 Store at 20°–25°C (68°–77°F) [see USP Controlled Room Temperature]. Avoid excessive heat. Protect from freezing. Repackaged and Distributed By: Remedy Repack, Inc. 625 Kolter Dr. Suite #4 Indiana, PA 1-724-465-8762

Stato dell'autorizzazione:

Abbreviated New Drug Application

Scheda tecnica

TRIAMCINOLONE ACETONIDE- TRIAMCINOLONE ACETONIDE CREAM
REMEDYREPACK INC.
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DESCRIPTION
The topical corticosteroids constitute a class of primarily synthetic
steroids used as anti-
inflammatory and antipruritic agents. Triamcinolone acetonide is a
member of this class.
Chemically triamcinolone acetonide is pregna-1, 4-diene-3, 20-dione,
9-fluoro-11, 21-
dihydroxy-16, 17-[(1-methylethylidene) bis(oxy)]-(11β16α) Its
structural formula is:
Each gram of Triamcinolone Acetonide Cream USP, 0.025% contains 0.25
mg
triamcinolone acetonide USP in a cream base consisting of purified
water, emulsifying
wax, mineral oil, propylene glycol, sorbitol solution, cetyl
palmitate, sorbic acid, and
potassium sorbate.
Each gram of Triamcinolone Acetonide Cream USP, 0.1% contains 1 mg
triamcinolone
acetonide USP in a cream base consisting of purified water,
emulsifying wax, mineral oil,
propylene glycol, sorbitol solution, cetyl palmitate, sorbic acid, and
potassium sorbate.
Each gram of Triamcinolone Acetonide Cream USP, 0.5% contains 5 mg
triamcinolone
acetonide USP in a cream base consisting of purified water,
emulsifying wax, mineral oil,
propylene glycol, sorbitol solution, cetyl palmitate, sorbic acid, and
potassium sorbate.
CLINICAL PHARMACOLOGY
Topical corticosteroids share anti-inflammatory, antipruritic and
vasoconstrictive actions.
The mechanism of anti-inflammatory activity of the topical
corticosteroids is unclear.
Various laboratory methods, including vasoconstrictor assays, are used
to compare and
predict potencies and/or clinical efficacies of the topical
corticosteroids. There is some
evidence to suggest that a recognizable correlation exists between
vasoconstrictor
potency and therapeutic efficacy in man.
_Pharmacokinetics_
The extent of percutaneous absorption of topical corticosteroids is
determined by many
factors including the vehicle, the integrity of the epidermal barrier,
and the use of
occlusive dressings.
Topical corticosteroids can be absorbed from normal intact skin.
Inflammation and/or
other dis