TENORET 50 TABLET

Nazione: Singapore

Lingua: inglese

Fonte: HSA (Health Sciences Authority)

Principio attivo:

ATENOLOL; CHLORTHALIDONE

Commercializzato da:

ASTRAZENECA SINGAPORE PTE LTD

Codice ATC:

C07CB03

Dosaggio:

50 mg

Forma farmaceutica:

TABLET, FILM COATED

Composizione:

ATENOLOL 50 mg; CHLORTHALIDONE 12.5 mg

Via di somministrazione:

ORAL

Tipo di ricetta:

Prescription Only

Prodotto da:

ASTRAZENECA UK LTD

Stato dell'autorizzazione:

ACTIVE

Data dell'autorizzazione:

1988-05-06

Foglio illustrativo

TENORET 50 
_Atenolol/chlorthalidone _
TABLETS 

COMPOSITION

Tablets containing 50 mg of Atenolol Ph. Eur. and 12.5 mg of
Chlorthalidone Ph. Eur. 

PHARMACEUTICAL FORM 

White, round, biconvex, film coated tablets 

THERAPEUTIC INDICATIONS 

i)   
Hypertension. 
ii)  
Hypertension in the elderly. 

POSOLOGY AND METHOD OF ADMINISTRATION 

ADULTS 

One tablet daily. 

ELDERLY 

One tablet daily. Older patients with hypertension who do not respond
to low dose therapy 
with a single agent or where full doses of both may be considered
inappropriate, should have 
a satisfactory response to a single tablet daily of Tenoret 50. Where
hypertensive control is 
not achieved, addition of a small dose of a third agent eg. as a
vasodilator, may be 
appropriate. 

CHILDREN 

There is no paediatric experience with Tenoret 50, and for this reason
it is not recommended 
for children. 

RENAL FAILURE 

Caution should be exercised in patients with severe renal failure. The
dose should be reduced 
by decreasing the frequency of administration (see Special warnings
and precautions for use). 
Page 1 of 7 

CONTRAINDICATIONS 

Tenoret 50 should not be used in patients with any of the following:
known hypersensitivity 
to either component, bradycardia, cardiogenic shock, hypotension;
metabolic acidosis, severe 
peripheral arterial circulatory disturbances, second or third degree
heart block, sick sinus 
Syndrome, untreated phaeochromocytoma, uncontrolled heart failure. 

TENORET 50 MUST NOT BE GIVEN DURING PREGNANCY OR LACTATION. 

SPECIAL WARNINGS AND PRECAUTIONS FOR USE 

Due to its beta-blocker component Tenoret 50: 

-    
although contraindicated in uncontrolled heart failure (see
Contraindications), may  
be used in patients whose signs of heart failure have been controlled.
Caution must be 

exercised in patients whose cardiac reserve is poor. 

-    
may increase the number and duration of angina attacks in

Scheda tecnica

TENORET 50
_Atenolol/chlorthalidone _
TABLETS
COMPOSITION
Tablets containing 50 mg of Atenolol Ph. Eur. and 12.5 mg of
Chlorthalidone Ph. Eur.
PHARMACEUTICAL FORM
White, round, biconvex, film coated tablets
THERAPEUTIC INDICATIONS
i)
Hypertension.
ii)
Hypertension in the elderly.
POSOLOGY AND METHOD OF ADMINISTRATION
ADULTS
One tablet daily.
ELDERLY
One tablet daily. Older patients with hypertension who do not respond
to low dose therapy
with a single agent or where full doses of both may be considered
inappropriate, should have
a satisfactory response to a single tablet daily of Tenoret 50. Where
hypertensive control is
not achieved, addition of a small dose of a third agent eg. as a
vasodilator, may be
appropriate.
CHILDREN
There is no paediatric experience with Tenoret 50, and for this reason
it is not recommended
for children.
RENAL FAILURE
Caution should be exercised in patients with severe renal failure. The
dose should be reduced
by decreasing the frequency of administration (see Special warnings
and precautions for use).
Page 1 of 7
CONTRAINDICATIONS
Tenoret 50 should not be used in patients with any of the following:
known hypersensitivity
to either component, bradycardia, cardiogenic shock, hypotension;
metabolic acidosis, severe
peripheral arterial circulatory disturbances, second or third degree
heart block, sick sinus
Syndrome, untreated phaeochromocytoma, uncontrolled heart failure.
TENORET 50 MUST NOT BE GIVEN DURING PREGNANCY OR LACTATION.
SPECIAL WARNINGS AND PRECAUTIONS FOR USE
Due to its beta-blocker component Tenoret 50:
-
although contraindicated in uncontrolled heart failure (see
Contraindications), may
be used in patients whose signs of heart failure have been controlled.
Caution must be
exercised in patients whose cardiac reserve is poor.
-
may increase the number and duration of angina attacks in patients
with Prinzmetal's
angina due to unopposed alpha receptor mediated coronary artery
vasoconstriction.
Atenolol is a beta-1 selective beta-blocker; consequently the use of
Tenoret 50 may
be