Nazione: Canada
Lingua: inglese
Fonte: Health Canada
SALBUTAMOL (SALBUTAMOL SULFATE)
NU-PHARM INC
R03AC02
SALBUTAMOL
1MG
SOLUTION
SALBUTAMOL (SALBUTAMOL SULFATE) 1MG
INHALATION
2.5ML
Prescription
SELECTIVE BETA 2-ADRENERGIC AGONISTS
Active ingredient group (AIG) number: 0108887007; AHFS:
CANCELLED POST MARKET
2012-09-04
PRODUCT MONOGRAPH NU-SALBUTAMOL RESPIRATOR SOLUTIONS (Salbutamol Sulfate Solutions BP) NU-SALBUTAMOL Respirator Solution 50 mg/10 mL (5 mg/mL Salbutamol) NU-SALBUTAMOL Plastic Ampules 2.5 mg/2.5 mL (1 mg/mL Salbutamol) NU-SALBUTAMOL Plastic Ampules 5.0 mg/2.5 mL (2 mg/mL Salbutamol) Bronchodilator, Β 2 -adrenergic Stimulant NU PHARM Inc. 50 Mural Street, Units 1 & 2 Richmond Hill, Ontario DATE OF REVISION: L4B 1E4 December 16, 2004 Control # 094010 PRODUCT MONOGRAPH NU-SALBUTAMOL RESPIRATOR SOLUTIONS (Salbutamol Sulfate Solutions BP) NU-SALBUTAMOL Respirator Solution 50 mg/10 mL (5 mg/mL Salbutamol) NU-SALBUTAMOL Plastic Ampules 2.5 mg/2.5 mL (1 mg/mL Salbutamol) NU-SALBUTAMOL Plastic Ampules 5.0 mg/2.5 mL (2 mg/mL Salbutamol) THERAPEUTIC CLASSIFICATION Bronchodilator, β 2 -adrenergic Stimulant ACTIONS AND CLINICAL PHARMACOLOGY Salbutamol produces bronchodilation through stimulation of beta 2 -adrenergic receptors in bronchial smooth muscle, thereby causing relaxation of bronchial muscle fibres. This action is manifested by an improvement in pulmonary function as demonstrated by spirometric measurements. At therapeutic doses, salbutamol has little action on the beta 1 -adrenergic receptors in cardiac muscle (salbutamol inhalation aerosol and dry powder formulations). A measurable decrease in airway resistance is typically observed 5 to 15 minutes after inhalation of salbutamol. The maximum improvement in pulmonary function usually occurs 60 to 90 minutes after salbutamol treatment, and significant bronchodilator activity has been observed to persist for 3 to 6 hours. INDICATIONS AND CLINICAL USE NU-SALBUTAMOL Respirator Solutions (Salbutamol Sulfate Solution BP) are indicated for the treatment of severe bronchospasm associated with exacerbations of chronic bronchitis and bronchial asthma. They can be used by 'wet' nebulization. When administered through a nebulizer, NU-SALBUTAMOL Respirator Solutions (Salbutamol Sulfate Solution BP) should be used with compressed air or oxygen. - 2 - CONTRAINDICATIONS Hypersens Leggi il documento completo