Nazione: Malesia
Lingua: inglese
Fonte: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
POSACONAZOLE
MERCK SHARP & DOHME (MALAYSIA) SDN BHD
POSACONAZOLE
24tablet Tablets; 96tablet Tablets
N.V. ORGANON
_Consumer Medication Information Leaflet (RiMUP)_ NOXAFIL ® MODIFIED RELEASE TABLET Posaconazole (100mg) _ _ _ _ _ _ _ _ _ _ WHAT IS IN THIS LEAFLET 1. What NOXAFIL MODIFIED RELEASE TABLET is used for 2. How NOXAFIL MODIFIED RELEASE TABLET works 3. Before you take NOXAFIL MODIFIED RELEASE TABLET 4. How to take NOXAFIL MODIFIED RELEASE TABLET 5. While you are taking NOXAFIL MODIFIED RELEASE TABLET 6. Side effects 7. Storage and Disposal of NOXAFIL MODIFIED RELEASE TABLET 8. Product description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT NOXAFIL MODIFIED RELEASE TABLET IS USED FOR NOXAFIL MODIFIED RELEASE TABLET is used for: • The treatment of invasive aspergillosis, a fungal infection caused by a fungus called aspergillus • The treatment of other serious fungal infections called fusariosis, zygomycosis, chromoblastomycosis and mycetoma. These types of fungal infections usually occur in some patients who may have lowered resistance to infection due to poor immunity. Treatment of these serious fungal infections with NOXAFIL MODIFIED RELEASE TABLET is usually reserved for patients who do not respond to or cannot tolerate other medicines used to treat these types of fungal infections. NOXAFIL MODIFIED RELEASE TABLET is also used to treat coccidioidomycosis, a rare and serious fungal infection. NOXAFIL MODIFIED RELEASE TABLET is also used to prevent fungal infections, such as yeasts and moulds, from occurring in patients who are at high-risk of developing these infections. Your doctor may have prescribed NOXAFIL MODIFIED RELEASE TABLET for another reason. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY NOXAFIL MODIFIED RELEASE TABLET HAS BEEN PRESCRIBED FOR YOU. This medicine is available only with a doctor's prescription. HOW NOXAFIL MODIFIED RELEASE TABLET WORKS NOXAFIL MODIFIED RELEASE TABLET contains the active ingredient, posaconazole. Posaconazole is a medicine that belongs to the triazole group of antifungal medicines. NOXAFIL MODIFIED RELEASE TABLET works by killing or sto Leggi il documento completo
NOXAFIL ® 100 mg MODIFIED RELEASE TABLET Product Information NAME OF THE MEDICINE Posaconazole Posaconazole is a broad spectrum triazole antifungal compound with a molecular formula of C 37H42F2N8O4 yielding a molecular weight of 700.8. The chemical str ucture, which possesses four chiral centres, two R and two S, and chemical name are illustrated below: O N N N N O F F N N O C H 3 H3C O H N N CAS INDEX NAME: D -threo -Pentitol, 2,5 -anhydro -1,3,4 -trideoxy -2 -C -(2,4 - difluorophenyl) -4 -[[4 -[4 -[4 -[1 -[(1S,2S) -1 -ethy l- 2 -hydropropyl] -1,5 -dihydro -5 -oxo- 4H-1,2,4 - triazol -4 -yl]phenyl] -1 -piperazinyl]phenoxy]methyl] -1 -(1H -1,2,4 -triazol -1 -yl) CAS RN 171228- 49-2. IUPAC NAME: 4 -4 -[4 -(4 -{(3R, 5R) -5 -(2,4 -difluorophenyl) -5 -(1H -1,2,4 -triazol -1 - ylmethyl)tetrahydro- 3-furanyl]methoxyphenyl)piperazino]phenyl -1 -[(1S,2S) -1 -ethyl -2 - hydroxypropyl] -4,5 -dihydro- 1H-1,2,4 -triazol -5 -one. DESCRIPTION Posaconazole is a white to off -white crystalline powder. It has a melting range of 164 o – 165 oC and is insoluble in water. Noxafil ® 100 mg modified release tablet is a yellow- coated, capsule- shaped tablet debossed with “100” on one side containing 100mg of posaconazole. Leggi il documento completo