Country: Ástralía
Tungumál: enska
Heimild: APVMA (Australian Pesticides and Veterinary Medicines Authority)
TRIMETHOPRIM; SULFADIAZINE
ELANCO AUSTRALASIA PTY LTD
trimethoprim(80mg/Tb)+sulfadiazine(400mg/Tb)
ORAL TABLET
TRIMETHOPRIM PYRIMIDINE Active 80.0 mg/Tb; SULFADIAZINE SULFANYL Active 400.0 mg/Tb
100 Tablets
VM - Veterinary Medicine
BAYER AUSTRALIA
DOG - LARGE | DOG - MEDIUM | CASTRATE
ANTIBIOTIC & RELATED
BACTERIAL INFECTION | INFECTIONS OF THE ALIMENTARY TRACT | INFECTIONS OF THE RESPIRATORY TRACT | INFECTIONS OF THE UROGENITAL TRACT | ACUTE RESPIRATORY INFECTIONS | AMOXYCILLIN SENSITIVE BACTERIA | ASSOCIATED WITH VIRAL DISEASE | BRONCHISEPTICA | BRONCHITIS | CYSTITIS | GRAM NEGATIVE ORGANISMS | GRAM POSITIVE ORGANISMS | METRITIS | NEPHRITIS | PHARYNGITIS | PNEUMONIA | POST PARTURIENT BACTERIAL INFE | PRIMARY BACTERIAL INFECTION | SULFADIAZINE SENSITIVE BACTERI | TONSILLITIS | TRIMETHOPRIM SENSITIVE BACTERI | TYLOSIN SENSITIVE BACTERIA
Poison schedule: 4; Withholding period: WHP: NOT APPLICABLE; Host/pest details: DOG - LARGE: [BACTERIAL INFECTION, INFECTIONS OF THE ALIMENTARY TRACT, INFECTIONS OF THE RESPIRATORY TRACT, INFECTIONS OF THE UROGENITAL TRACT]; DOG - MEDIUM: [BACTERIAL INFECTION, INFECTIONS OF THE ALIMENTARY TRACT, INFECTIONS OF THE RESPIRATORY TRACT, INFECTIONS OF THE UROGENITAL TRACT]; Poison schedule: 4; Withholding period: ; Host/pest details: DOG - LARGE: [BACTERIAL INFECTION, INFECTIONS OF THE ALIMENTARY TRACT, INFECTIONS OF THE RESPIRATORY TRACT, INFECTIONS OF THE UROGENITAL TRACT]; DOG - MEDIUM: [BACTERIAL INFECTION, INFECTIONS OF THE ALIMENTARY TRACT, INFECTIONS OF THE RESPIRATORY TRACT, INFECTIONS OF THE UROGENITAL TRACT]; For the treatment of infections sensitive to trimethoprim /sulfadiazine sensitive micro-organisms, especially infections of the respiratory tract, urogenital tract and alimentary tract.Do not give to cats. Contra-indicated in severe hepatic or renal impairment. Teratogenetic at high doses in some species. Drug interactions will displace other protein based drugs. See ADVERSE EFFECTS on leaflet also.
Stopped
2023-07-01
\CAUTION I S4 SUPPLY WITHOUT PRESCRIPTION ILLEGAL KEEP OUT OF REACH OF CHILDREN FOR ANIMAL TREATMENT ONLY TRIMETHOTAB 480 - Trimethoprim 80mg and Sulfadiazine 400mg per Antibacterial Tablet DIRECTIONS FOR USE Tr imethotab-4BO tablets should not be given to cats . For the treatment of medium sized and large dogs. For oral use only. 30mg of combined active constituents / kg bodyweight daily equivalent to 1 tablet per 16kg bodyweight TRIMETHOTAB 120 - Trimethoprim 20mg and Sulfadiazine 100mg per Antibac- terial Tablet TRIMETHOTAB 480 - Trimethoprim 80mg and Sulfadiazine 400mg per Antibac- terial Tablet DESCRIPTION White cross scored tablets . Each tablet contains: Trimethoprim Sulfadiazine BOmg 400mg .~ BOMACLABORATORIES PTY LTD '-.'" Unit3,14 Anella Avenue , CastleHill, NSW2154, Australia Preferably the dose should be divided in half and given twice daily. Repeat treatment for 5 days or for at least 2 days after the symptoms have subsided. Trimethotab veterinary preparations are formulated with synthetic chemotherapeutic agents Trimethoprim and Sulfadiazine in a ratio of 1 : 5. MODE OF ACTION The combination acts by inhibiting sequential steps in the biosyn- thetic pathway that is used by micro-organisms in their synthesis of folate co-factors. Sulfadiazine inhibits the incorporation of para- aminobenzoic acid (PABA) into folic acid and Trimethoprim inhibits the enzyme dihydrofolate reductase , which converts dihydrofolic acid into tetrahydro folic acid. Dogs up to Bkg 16kg 24kg 32kg 40kg 4Bkg 1/2 tablet 1 tablets 1 1/2 tablets 2 tablets 2 1/2 tablets 3 tablets In comb ination the two active constituents have a bactericidal activity against most gram-positive and gram-negative pathogenic bacteria including Staphylococci, Streptococci, E.coli, Pasteurella spp, Bordetella spp, Salmonella spp, Proteus spp, Klebsiella spp, Bacillis anthracis, Corynebacterium spp, Vibriospp and Haemophilus spp. Pseudomonas aerug inosa , Erys ipelothrix , Leptospira and Mycobacterium tube rculosis are not sensitive . INDICATIONS For the Lestu allt skjalið
MATERIAL SAFETY DATA SHEET Page 1 of 5 http://www.bomac.co.nz/Prduct%20pgs/MSDS/TRIMETHO%20480.html 28/08/2000 MATERIAL SAFETY DATA SHEET (MSDS) _BOMAC LABORATORIES LIMITED URGES RECIPIENT OF THIS MSDS TO STUDY IT CAREFULLY_ _TO BECOME AWARE OF, AND UNDERSTAND, THE HAZARDS ASSOCIATED WITH THE PRODUCT._ _TO PROMOTE SAFE HANDLING, EACH RECIPIENT SHOULD NOTIFY ITS EMPLOYEES, AGENTS AND OTHERS WHO _ _WILL USE THIS MATERIAL AND ANY OTHER INFORMATION REGARDING HAZARDS OR SAFETY._ Page 1 of 3 ___________________________________________________________________________ IDENTIFICATION ___________________________________________________________________________ Product name: Trimethotab 480 UN Number: N/A Other Names: N/A Dangerous Goods Class:N/A Animal Remedies Board (ARB) Subsidiary Risk: N/A Product Licence Number:7013 HAZCHEM Code: N/A Toxic Substances Schedule:N/A Use: For the treatment and control of infections due to Sulphadiazine/Trimethoprim sensitive microorganisms in dogs especially infections of the respiratory, urogenital and alimentary tracts. Physical Description: A white, round, cross- scored tablet with a bevelled edge. Active Ingredients: Sulphadiazine 400mg CAS* No. 68-35-9 Trimethoprim 80mg CAS* No. 738-70-5 Manufacturer: BOMAC Laboratories Ltd Cnr Wiri Station Road & Hobill Avenue P O Box 76-369, Manukau City, Auckland, New Zealand Phone: (09) 262-3169 Facsimile: (09) 262-3008 ________________________________________ HEALTH HAZARD INFORMATION ________________________________________ MATERIAL SAFETY DATA SHEET Page 2 of 5 http://www.bomac.co.nz/Prduct%20pgs/MSDS/TRIMETHO%20480.html 28/08/2000 HEALTH EFFECTS Swallowed: Ingestion may cause nausea, vomiting, diarrhoea, headache, dizziness, drug fever, skin rashes and other allergic reactions. Eye: May cause transient stinging or redness if accidental eye contact occurs. Keratoconjuntivitis sicca (dry eye) which may be irreversible or acute, hypersensitivity reactions have been recorded. *CAS, Chemical Abstracts Service Regist Lestu allt skjalið