TP-TYLOFEN 500MGG POWDER

Country: Malasía

Tungumál: enska

Heimild: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Virkt innihaldsefni:

TYLOSIN TARTRATE

Fáanlegur frá:

Thye Pharma Sdn. Bhd

INN (Alþjóðlegt nafn):

TYLOSIN TARTRATE

Framleitt af:

Thye Pharma Sdn. Bhd

Vara einkenni

Veterinary Package Insert
TP-TYLOFEN
500MG/G
POWDER
(50%
Tylosin Tartrate)
PRODUCT DESCRIPTION
Off-white to light yellow colour powder.
PHARMACODYNAMICS & PHARMACOKINETICS
_Pharmacodynamics: _
Tylosin
is
a
macrolide
antibiotic
produced
by
a
strain
of
Streptomyces
fradiae.
It
exerts
its
antimicrobial effect by inhibiting protein synthesis
of susceptible micro-organisms.
_Pharmacokinetics: _
Absorption: Tylosin reaches maximal blood levels
between 1 and 3 hours after an oral dose. Minimal
or no blood levels remain 24 hours after an oral
dose.
Distribution: After oral doses were given to pigs,
tylosin
was
found
in
all
tissues,
between
30
minutes and two hours after administration, except
for the brain and spinal cord.
INDICATION
Pigs: For the prevention and control of enzootic
pneumonia, and scours caused by organisms (e.g.
Lawsonia intracellularis) sensitive to tylosin.
Chickens/ Turkeys: For the control of Mycoplasma
synoviae airsacculitis in chickens and Mycoplasma
gallisepticum S6 in chickens and turkeys. In the
field tylosin has also proved useful in reducing the
level of infection following stress associated with
live vaccination.
As an aid in the control of outbreaks of necrotic
enteritis
in
chickens
caused
by
Clostridium
perfringens.
RECOMMENDED DOSAGE AND ADMINISTRATION
It is to be given orally. To be administered in drinking
water.
Recommendations for use in chickens and turkeys:
Product is administered in the drinking water at a
concentration of 1.1 g per litre.
As an aid in the control of outbreaks of necrotic
enteritis
caused
by
Clostridium
perfringens
in
chickens use the product in the drinking water for 5
days at a concentration of 0.3 g per litre water
(150ppm), to provide 20-50 mg/kg bw, depending
on the age and the water consumption of the birds.
Recommendations for use in pigs:
The product is administered in the drinking water
to provide 25 mg tylosin/kg bodyweight. This may
normally be achieved by adding 0.5 per litre.
To ensure a correct dosage, body weight should be
determined
as
accurately
as