Land: Kanada
Tungumál: enska
Heimild: Health Canada
SULFACETAMIDE SODIUM
ODAN LABORATORIES LTD
S01AB04
SULFACETAMIDE
10%
SOLUTION
SULFACETAMIDE SODIUM 10%
OPHTHALMIC
15ML
Prescription
ANTIBACTERIALS
Active ingredient group (AIG) number: 0106092001; AHFS:
APPROVED
2015-10-14
PRESCRIBINGINFORMATION PR ODAN-SULFACETAMIDE SULFACETAMIDE SODIUM OPHTHALMIC SOLUTION, USP 10 % ANTIBACTERIAL ODAN LABORATORIES LTD. 325 Stillview Ave., Pointe-Claire, Québec H9R 2Y6 Control No: 220032 Date of Revision: October 18, 2018 www.odanlab.com 2 PRESCRIBING INFORMATION PR ODAN-SULFACETAMIDE SULFACETAMIDE SODIUM OPHTHALMIC SOLUTION, USP 10 % THERAPEUTIC CLASSIFICATION Antibacterial ACTION AND CLINICAL PHARMACOLOGY The sulfonamides are bacteriostatic agents and the spectrum of activity is similar for all. Sulfonamides inhibit bacterial synthesis of dihydrofolic acid by preventing the condensation of the pteridine with aminobenzoic acid through competitive inhibition of the enzyme dihydropteroate synthetase. Resistant strains have altered dihydropteroate synthetase with reduced affinity for sulfonamides or produce increased quantities of aminobenzoic acid. Topically applied sulfonamides are considered active against susceptible strains of the following common bacterial eye pathogens: Escherichia coli, Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus (viridans group), Haemophilus influenzae, Klebsiella species, and Enterobacter species. Topically applied sulfonamides do not provide adequate coverage against Neisseria species, Serratia marcescens and Pseudomonas aeruginosa. A significant percentage of staphylococcal isolates are completely resistant to sulfadrugs. INDICATIONS For the treatment of conjunctivitis and other superficial ocular infections due to susceptible microorganisms and as an adjunctive in systemic sulfonamide therapy of trachoma: Escherichia coli, Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus (viridans group), Haemophilus influenzae, Klebsiella species, and Enterobacter species. Topically applied sulfonamides do not provide adequate coverage against Neisseria species, Serratia marcescens and Pseudomonas aeruginosa. A significant percentage of staphylococcal isolates are completely resistant to sulfadrugs. To reduce the development of drug-resistant bacteria a Lestu allt skjalið