NP THYROID 90 levothyroxine liothyronine tablet

Country: Bandaríkin

Tungumál: enska

Heimild: NLM (National Library of Medicine)

Virkt innihaldsefni:

LEVOTHYROXINE (UNII: Q51BO43MG4) (LEVOTHYROXINE - UNII:Q51BO43MG4)

Fáanlegur frá:

Medsource Pharmaceuticals

INN (Alþjóðlegt nafn):

LEVOTHYROXINE

Samsetning:

LEVOTHYROXINE 57 ug

Gerð lyfseðils:

PRESCRIPTION DRUG

Leyfisstaða:

unapproved drug other

Vara einkenni

NP THYROID 90- LEVOTHYROXINE, LIOTHYRONINE TABLET
MEDSOURCE PHARMACEUTICALS
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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NP THYROID 90
NP Thyroid (thyroid tablets, USP) for oral use is a natural
preparation derived from porcine thyroid
glands. They contain both tetraiodothyronine sodium (T4 levothyroxine)
and triiodothyronine sodium
(T3 liothyronine) providing 38 mcg levothyroxine (T4) and 9 mcg
liothyronine (T3) per grain of thyroid
(or per 65 mg of the labeled amount of thyroid). The inactive
ingredients are calcium stearate, dextrose
monohydrate, maltodextrin and mineral oil.
CLINICAL PHARMACOLOGY: The steps in the synthesis of the thyroid
hormones are controlled by
thyrotropin (Thyroid Stimulating Hormone, TSH) secreted by the
anterior pituitary. This hormone’s
secretion is in turn controlled by a feedback mechanism effected by
the thyroid hormones themselves
and by thyrotropin releasing hormone (TRH), a tripeptide of
hypothalamic origin. Endogenous thyroid
hormone
secretion is suppressed when exogenous thyroid hormones are
administered to euthyroid individuals in
excess of the normal gland’s secretion. The mechanisms by which
thyroid hormones exert their
physiologic action are not well understood. These hormones enhance
oxygen consumption by most
tissues of the body, increase the basal metabolic rate, and the
metabolism of carbohydrates, lipids, and
proteins. Thus, they exert a profound influence on every organ system
in the body and are of particular
importance in the development of the central nervous system. The
normal thyroid gland contains
approximately 200 mcg of levothyroxine (T4) per gram of gland, and 15
mcg of liodothyronine (T3) per
gram. The ratio of these two hormones in the circulation does not
represent the ratio in the thyroid
gland, since about 80 percent of peripheral triiodothyronine comes
from monodeiodination of
levothyroxine. Periphe