Land: Indónesía
Tungumál: indónesíska
Heimild: Badan Pengawas Obat dan Makanan RI - Indonesian Food and Drug Supervisory Agency
METRONIDAZOLE
AVENTIS PHARMA - Indonesia
METRONIDAZOLE
500 MG
INFUS
DUS, 40 KANTONG PLASTIK @ 100 ML
BAXTER HEALTHCARE S.A. - Ireland
2020-12-03
FLAGYL ® METRONIDAZOLE COMPOSITION FLAGYL ® lnfus : contains 500 mg metronidazole/100 ml infusion PHARMACOLOGICAL PROPERTIES Trichomoniacide, anaerobicide. Disposition of metronidazole given orally or by intravenous injection remains constant, with average elimination time of 8 hours in healthy man. Metronidazole was detected in cerebrospinal fluid, saliva and breast milk in same concentration as in plasma. Metronidazole was also detected in the pus of hepatic abscess. INDICATIONS - Urethritis and vaginitis due to _Trichomonas vagina/is_ - Amoebiasis _(Intestinal and hepatic amoebiasis)_ - Prevention of post-operative anaerobic infections - Giardiasis due to _Giardia lambliasis_ DOSAGE AND ADMINISTRATION Intravenous infusion at the rate of 5 ml per minute has to be replaced soon with oral administration. Treatment of infections in which bacteria have been identified: In patient whom oral medication is not possible. Adult and children< 12 years. Adult: 500 mg by i.v. infusion every 8 hours. Children: 7.5 mg/kg body-weight every 8 hours. Prevention of post operative abdominal infections ( especia I ly colorecta I), gynaecology. Adult: 500 mg by i.v. infusion before operation, followed by 500 mg oral medication every 8 hours as soon as this becomes feasible. Children: 7.5 mg/kg body-weight (1.5 ml/kg body-weight) every 8 hours. WARNINGS AND PRECAUTIONS - Used with caution in nursing mothers as metronidazole is excreted in breast milk, during SOOMG/100ML .... SANOFI � first and second trimesters of pregnancy as metronidazole crosses the placental barrier. - Used with caution in patients with central nervous system diseases. Disturbances of central nervous system has been reported in some cases but disappeared if therapy is discontinued or dose decreased. - Taking alcohol during metronidazole therapy may cause abdominal cramps, nausea, vomiting, headache, flushing. - In prolonged metronidazole administration, it is recommended to perform hematological tests. - Dosage should be reduced and administered with caution Lestu allt skjalið