Country: Bretland
Tungumál: enska
Heimild: VMD (Veterinary Medicines Directorate)
Erythromycin
Ceva Animal Health Ltd
Erythromycin
Expired
Summary of Product Characteristics 1. Name of Veterinary Medicinal Product Erythrocin Proportioner. 2. Composition g/100 g Active ingredient: Erythromycin phosphate 29.641 Other ingredients: Amaranth 0.025 Benzethonium chloride (antimicrobial preservative) 12.860 3. Pharmaceutical Form A soluble, fine, off-white powder for dissolution in water and subsequent oral administration. 4. Pharmacological Properties Erythromycin is a macrolide antibiotic with a bacteriostatic action against a wide range of bacteria, although it also has a bactericidal action against certain pathogenic organisms. It is highly active against gram-positive bacteria and at low concentrations it inhibits many other types of micro- organisms. In addition to the gram-positive bacteria, most strains of Neisseria and Haemophilus are sensitive as are some strains of Bordetella, Brucella, Pasteurella, Listeria, Actinomyces, Mycoplasma, Rickettsia, certain large viruses and Treponema pallidum. Erythromycin exerts its effect only against multiplying bacteria. It inhibits protein synthesis by binding to 50 S ribosomal subunits of sensitive micro- organisms. Certain resistant micro-organisms with mutational changes in components of this subunit of the ribosome fail to bind the drug. Erythromycin is absorbed rapidly when administered orally and diffusion occurs into most tissues and fluids. Elimination of erythromycin occurs primarily through hepatic metabolism and the remainder is excreted in active form in the urine and bile. 5. Clinical Particulars 5.0 Target species: Broilers up to 6 days of Lestu allt skjalið