Country: Bretland
Tungumál: enska
Heimild: MHRA (Medicines & Healthcare Products Regulatory Agency)
Carbimazole
Mawdsley-Brooks & Company Ltd
H03BB01
Carbimazole
20mg
Oral tablet
Oral
No Controlled Drug Status
Valid as a prescribable product
BNF: 06020200
Do not change the dosage without consulting your doctor first Some improvement is usually felt within one to three weeks. However, full beneficial effects usually take four to eight weeks In order to maintain control of the thyroid gland, you may need to continue to take Carbimazole tablets for several months. Your doctor will decide when treatment can be stopped. Your doctor may ask you to have occasional blood tests to help determine how you are responding to treatment Radio-iodine is another treatment for hyperthyroidism. If you need radio-iodine treatment, your doctor will tell you to stop taking Carbimazole temporarily. RECOMMENDED DOSE ADULTS AND THE ELDERLY: the recommended starting dose is one to three 20 mg tablets or four to twelve 5 mg tablets daily. Once control is achieved your doctor will gradually reduce your dose to one to three 5 mg tablets each day. USE IN CHILDREN: the recommended starting dose is three 5 mg tablets daily. IF YOU TAKE MORE CARBIMAZOLE THAN YOU SHOULD If you take more Carbimazole than you should, contact your doctor or nearest hospital emergency department immediately. Take the container and any remaining tablets with you. IF YOU FORGET TO TAKE CARBIMAZOLE If you forget a dose, take it as soon as you remember. If it is time for your next dose, take both doses together. If you have any further questions of the use of this medicine ask your doctor or pharmacist. Like all medicines, Carbimazole can cause side effects, although not everybody gets them. SERIOUS SIDE EFFECTS: ALLERGIC REACTIONS If you have an allergic reaction, stop taking Carbimazole and see a doctor straight away. The signs may include: sudden rash, swelling or difficulty breathing. Stop taking Carbimazole and see a doctor straight away if you notice any of the following side effects: sore throat mouth ulcers high temperature or fever itching increased bruising or bleeding tendency significant tiredness you are feeling generally unwell or think that you may have an infecti Lestu allt skjalið
SUMMARY OF PRODUCT CHARACTERISTICS 1 NAME OF THE MEDICINAL PRODUCT Carbimazole 20mg Tablets 2 QUALITATIVE AND QUANTITATIVE COMPOSITION Each Carbimazole 20mg tablet contains 20mg of carbimazole. Excipients with known effect: lactose anhydrous 295.750mg. For the full list of excipients, see section 6.1. 3 PHARMACEUTICAL FORM Tablet. White coloured, round-shaped, uncoated tablets debossed “CARB” on one side and “20” on the other side having diameter 9.60mm. 4 CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS Carbimazole is an anti-thyroid agent. It is indicated in adults and children in all conditions where reduction of thyroid function is required. Such conditions are: 1. Hyperthyroidism 2. Preparation for thyroidectomy in hyperthyroidism. 3. Therapy prior to and post radio-iodine treatment. 4.2 POSOLOGY AND METHOD OF ADMINISTRATION Posology Carbimazole should only be administered if hyperthyroidism has been confirmed by laboratory tests. Adults The initial dose is in the range 20 - 60 mg, taken as two to three divided doses. The dose should be titrated against thyroid function until the patient is euthyroid in order to reduce the risk of over-treatment and resultant hypothyroidism. Subsequent therapy may then be administered in one of two ways. _Maintenance regimen:_ Final dosage is usually in the range 5 - 15 mg per day, which may be taken as a single daily dose. Therapy should be continued for at least six, and up to eighteen months. Serial thyroid function monitoring is recommended, together with appropriate dosage modification in order to maintain a euthyroid state. _Blocking-replacement regimen:_ Dosage is maintained at the initial level, i.e. 20 - 60 mg per day, and supplemental L-thyroxine, 50 - 150 mcg per day, is administered concomitantly, in order to prevent hypothyroidism. Therapy should be continued for at least six months, and up to eighteen months. Where a single dosage of less than 20 mg is recommended, it is intended that Carbimazole 5 mg Tablets should be taken. Elderly No special dosage r Lestu allt skjalið