Negara: Malaysia
Bahasa: Inggris
Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
TYLOSIN TARTRATE
GENPHARMA SDN. BHD
TYLOSIN TARTRATE
120.00 mcg/mL
PAHANG PHARMACY SDN. BHD.
[Draft of Package Insert] FOR ANIMAL USE ONLY TYLOSIN-100 WATER SOLUBLE POWDER CONTENT: Each sachet (120 g) contains, Tylosin (as tartrate) ……………………………….100 g PRODUCT DESCRIPTION: A light yellow powder. PHARMACODYNAMICS: Tylosin is a macrolide antibiotic produced by a strain of_ Streptomyces fradiae._ It exerts its antimicrobial effect by inhibiting protein synthesis of susceptible micro-organisms. The tylosin spectrum of activity includes amongst others Gram-positive bacteria, some Gram – negative strains such as_ Pasteurella_, and_ Mycoplasma spp_. PHARMACOKINETICS: In most species peak plasma concentrations have been attained 1 to 2 hours after administration of tylosin. Compared to plasma levels clearly higher tissue concentrations have been observed. Tylosin was extensively metabolised. Most of the residues are excreted in faeces predominantly consisting of tylosin (factor A), relomycin (factor D) and dihydrodesmycosin. INDICATION: Calves - Treatment and prevention of pneumonia caused by_ Mycoplasma spp_ when the disease has been established in the herd. Pigs - Treatment and prevention of enzootic pneumonia caused by_ Mycoplasma hyopneumoniae_ and _Mycoplasma hyorhinis_ when the disease has been established in the herd. Chickens - Treatment and prevention of chronic respiratory diseases (CRD) caused by_ Mycoplasma_ _gallisepticum_ and_ Mycoplasma synoviae_ when the disease has been established in the flock. - Treatment and prevention of necrotic enteritis caused by_ Clostridium perfringens_ when the disease has been established in the flock. Turkeys - Treatment and prevention of infectious sinusitis caused by_ Mycoplasma gallisepticum._ When the disease has been established in the flock. DOSAGE & ADMINISTRATION: Oral administration through the drinking water. In calves the product can also be administered through milk or milk replacer. 1 gram of the veterinary medicinal product corresponds to 0.833 gram of tylosin. The dosages are as follows: Calves: 10 – 20 mg tylosin per kg BW ( Baca dokumen lengkapnya