Trihexyphenidyl 2mg tablets

Negara: Inggris

Bahasa: Inggris

Sumber: MHRA (Medicines & Healthcare Products Regulatory Agency)

Bahan aktif:

Trihexyphenidyl hydrochloride

Tersedia dari:

Accord-UK Ltd

Kode ATC:

N04AA01

INN (Nama Internasional):

Trihexyphenidyl hydrochloride

Dosis:

2mg

Bentuk farmasi:

Oral tablet

Rute administrasi :

Oral

Kelas:

No Controlled Drug Status

Jenis Resep:

Valid as a prescribable product

Ringkasan produk:

BNF: 04090200; GTIN: 5012617018878

Selebaran informasi

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If you forget to take Trihexyphenidyl
Tablets
If you forget to take a dose of this medicine, take it as soon
as you remember. However, if it is almost time for the next
dose, skip the missed dose and take the next dose at the
usual time. DO NOT TAKE TWO DOSES AT THE SAME TIME.
4
.
POSSIBLE SIDE EFFECTS
30 – 50% of patients may experience dry mouth,
constipation, blurred vision, dizziness and stomach upset.
If any of the following occur STOP TAKING the tablets
IMMEDIATELY and contact your doctor, as they may be
signs of an allergic reaction:
• shortness of breath, blocked nose, rash, itching, swollen
face or lips (could happen to more than 1 in 100 people,
but less than 1 in 10)
The following other side-effects have been reported with
trihexyphenidyl:
Uncommon effects (that could happen to more than 1 in
100 people, but less than 1 in 10):
• difficulty in passing urine
• faster heart beat
• nervousness
• high doses of this medicine may cause excitement, feeling
of great happiness, agitation or confusion, hallucinations,
restlessness, difficulty sleeping, change in your mental
Like all medicines, this medicine can cause side effects,
although not everybody gets them.
6
.
5. HOW TO STORE TRIHEXYPHENIDYL TABLETS
KEEP ALL MEDICINES OUT OF THE SIGHT AND REACH OF CHILDREN.
FURTHER INFORMATION
Ingredients
Each Trihexyphenidyl 2mg Tablet contains 2mg of
trihexyphenidyl hydrochloride.
Other ingredients are magnesium stearate, maize starch,
pregelatinised maize starch and lactose.
W
hat Trihexyphenidyl
Tablets look like
The tablets are round and white with a breakline on one side.
They are available in pack sizes of 28, 30, 42, 50, 56, 60, 84,
90, 100, 112, 250, 500 and 1000 tablets. (Not all pack sizes
may be marketed).
W
ho makes this medicine and holds the Product Licence:
The Product Licence Holder is Crescent Pharma Limited,
Units 3 & 4, Quidhampton

Karakteristik produk

SUMMARY OF PRODUCT CHARACTERISTICS
1
NAME OF THE MEDICINAL PRODUCT
Trihexyphenidyl 2mg Tablets
2
QUALITATIVE AND QUANTITATIVE COMPOSITION
Each tablet contains 2mg of trihexyphenidyl hydrochloride
Excipient(s) with known effect
Lactose
For the full list of excipients, see section 6.1.
3
PHARMACEUTICAL FORM
White, flat bevel edged tablets with a breakline.
4
CLINICAL PARTICULARS
4.1
THERAPEUTIC INDICATIONS
1. Treatment of parkinsonism
2. Prevention and control of drug-induced extrapyramidal symptoms
(excluding tardive dyskinesia)
4.2
POSOLOGY AND METHOD OF ADMINISTRATION
Posology
_Adults only: _Optimal dosage should always be determined empirically,
usually
by initiating therapy at a relatively low level and by subsequent
graduated
increments._ _
The usual dosage for Parkinsonism is
6 - 10 mg per day although some
patients chiefly in the post-encephalitic group may require an average
total
dose of 12 - 15 mg daily. It should be given orally either three or
four times a
day at mealtimes.
Normal dosage for drug-induced Parkinsonism is usually between 5 mg
and
15 mg per day, although some cases have been controlled by 1 mg daily.
In all cases, trihexyphenidyl dosage should be increased or decreased
only by
small increments over a period of several days. In initial therapy the
dose
should be 1mg the first day, 2mg the second day with further increases
of
2mg per day at three to five-day intervals until the optimum dose is
reached.
If patients are already being treated with other parasympathetic
inhibitors,
trihexyphenidyl should be substituted as part of the therapy. When
trihexyphenidyl is used concomitantly with levodopa the usual dose of
each
may need to be reduced. Careful adjustment is necessary, depending on
side
effects and the degree of symptom control. Trihexyphenidyl dosage of
3-6mg
daily in divided doses, is usually adequate.
Trihexyphenidyl may be taken before or after meals according to the
way the
patient reacts. If trihexyphenidyl tends to dry the mouth excessively,
it may
be better to take it before mea