Negara: Amerika Serikat
Bahasa: Inggris
Sumber: NLM (National Library of Medicine)
Fenbendazole (UNII: 621BVT9M36) (Fenbendazole - UNII:621BVT9M36)
Schering Corporation
Fenbendazole
Fenbendazole 100 mg in 1 g
ORAL
OTC
Panacur® Paste 10% is indicated for the treatment and control of large strongyles (Strongylus edentatus, S. equinus, S. vulgaris ), encysted early 3rd stage (hypobiotic), late 3rd stage and 4th stage cyathostome larvae, small strongyles, pinworms (Oxyuris equi ), ascarids (Parascaris equorum ), and for the control of arteritis caused by 4th stage larvae of Strongylus vulgaris in horses.
Panacur® Paste 10% Equine Dewormer is supplied in 25 gram syringes. Store at or below 25°C (77°F). HOW SUPPLIED: Panacur® Paste 10% Equine Dewormer is supplied in 57 gram syringes, 5 per carton. Store at or below 25°C (77°F).
New Animal Drug Application
PANACUR- FENBENDAZOLE PASTE SCHERING CORPORATION ---------- PANACUR (FENBENDAZOLE) PASTE 10% (100 MG/G) EQUINE DEWORMER DESCRIPTION: Panacur (fenbendazole) Paste 10% contains the active anthelmintic, fenbendazole. The chemical name of fenbendazole is methyl 5-(phenylthio)-2-benzimidazole carbamate. The chemical structure is: Each gram of Panacur Paste 10% contains 100 mg of fenbendazole and is flavored with artificial apple-cinnamon liquid. ACTIONS: The antiparasitic action of Panacur Paste 10% is believed to be due to the inhibition of energy metabolism in the parasite. INDICATIONS: Panacur Paste 10% is indicated for the treatment and control of large strongyles (_Strongylus edentatus, S. equinus, S. vulgaris_), encysted early 3rd stage (hypobiotic), late 3rd stage and 4th stage cyathostome larvae, small strongyles, pinworms (_Oxyuris_ _equi_), ascarids (_Parascaris equorum_), and for the control of arteritis caused by 4th stage larvae of _Strongylus vulgaris_ in horses. PRECAUTIONS: Side effects associated with Panacur Paste 10% could not be established in well- ® ® ® ® ® ® controlled safety studies in horses with single doses as high as 454 mg/lb (1,000 mg/kg) and 15 consecutive daily doses of 22.7 mg/lb (50 mg/kg). Particularly with higher doses, the lethal action of fenbendazole may cause the release of antigens by the dying parasites. This phenomenon may result in either a local or systemic hypersensitivity reaction. As with any drug, these reactions should be treated symptomatically. Panacur Paste 10% has been evaluated for safety in pregnant mares during all stages of gestation with doses as high as 11.4 mg/lb (25 mg/kg) and in stallions with doses as high as 11.4 mg/lb (25 mg/kg). No adverse effects on reproduction were detected. The recommended dose for control of 4th stage _Strongylus vulgaris_ larvae, 4.6 mg/lb (10 mg/kg) daily for 5 consecutive days, has not been evaluated for safety in stallions or pregnant mares. WARNINGS: NOT FOR USE IN HUMANS. KEEP OUT OF REACH OF CHILDREN. The Safety Data Baca dokumen lengkapnya