NP PREDNISOLONE 5MG TABLET

Negara: Malaysia

Bahasa: Inggris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

PREDNISOLONE

Tersedia dari:

Noripharma Sdn. Bhd.

INN (Nama Internasional):

PREDNISOLONE

Unit dalam paket:

10 Tablet Tablets; 30 Tablet Tablets; 500 Tablet Tablets; 1000 Tablet Tablets; 100 Tablet Tablets

Diproduksi oleh:

Noripharma Sdn. Bhd.

Selebaran informasi

Consumer Medication Information Leaflet
PREDNISOLONE TABLET
Prednisolone/ Prednisolone Tablets 5mg
Page | 1
WHAT IS IN THIS LEAFLET
1.
What
is
Prednisolone
Tablet is used for
2.
How Prednisolone Tablet
works
3.
Before
you
use
Prednisolone Tablet
4.
How to use Prednisolone
Tablet
5.
While you are using it
6.
Side effects
7.
Storage
and
Disposal
of
Prednisolone Tablet
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10.
Date of Revision
WHAT IS PREDNISOLONE TABLET
USED FOR
Treating
allergies,
arthritis,
breathing
problems
(eg,
asthma),
certain
blood
disorders,
collagen
diseases
(eg,
lupus),
cancer
(eg,
leukemia), intestinal problems
(eg, ulcerative colitis), swelling
due
to
certain
conditions,
or
skin conditions. It may also be
used
for
other
conditions
as
determined by your doctor.
HOW
PREDNISOLONE
TABLET
WORKS
Prednisolone is a corticosteroid.
It
works
by
modifying
the
body's
immune
response
to
various
conditions
and
decreasing inflammation.
BEFORE YOU USE PREDNISOLONE
TABLET
-
When you must not use it
Do
not
take
Prednisolone
tablets if you:
• are allergic (hypersensitive) to
prednisolone or any of the other
ingredients
in
Prednisolone
tablets.
•
An
allergic
reaction
may
include
a
rash,
itching,
difficulty breathing or swelling
of
the
face,
lips,
throat
or
tongue.
• have cold sores that affect the
eyes
• have an untreated infection.
-
Before you start to use it
Consult your pharmacist before
taking Prednisolone tablets
if
you:
•
have
been
in
contact
with
anyone
who
has
chickenpox,
shingles
or
measles.
Contact
your
doctor
immediately
for
advice.
• have or have a family history
of diabetes or glaucoma
• have oestoporosis, high blood
pressure, a recent heart attack, a
stomach ulcer, an underactive
thyroid
gland,
epilepsy,
tuberculosis or septicaemia
•
have
taken
prednisolone
tablets (or a similar medicine)
before
and
had
muscular
problems (steroid myopathy)
• have heart, kidney or liver
problems/disease
• suffer or have suffered from
any mental illness
•
are
being
treated

Karakteristik produk

NP PREDNISOLONE TABLET
DESCRIPTION:
A white to off-white round shaped tablet with score line on one side.
COMPOSITION:
Each tablet contains Prednisolone 5mg.
ACTIONS & PHARMACOLOGY:
Prednisolone is an anti-inflammatory glucocorticoid. Glucocorticoids
decrease or prevent
tissue responses to inflammatory
processes, thereby reducing development of symptoms of
inflammation without affecting
the underlying cause. Glucocorticoids inhibit accumulation of
inflammatory cells, including macrophages and leukocytes, at sites of
inflammation. They also
inhibit
phagocytosis, lysosornal enzyme release, and synthesis and/or release
of several
chemical
mediators of inflammation.
Prednisolone is readily absorbed from the G.I.T. Plasma concentrations
of prednisolone are
obtained 1 or 2 hours after oral administration.
Prednisolone is extensively bound to plasma proteins. It has a
biological half-life lasting several
hours. Prednisolone is excreted in the urine as free and conjugated
metabolites, together with an
appreciable proportion of unchanged prednisolone. Prednisolone crosses
the placenta and small
amounts are excreted in breast milk.
INDICATIONS:
Asthma, severe allergic disturbances, leukemia, rheumatoid arthritis,
collagen diseases and
various inflammatory conditions. Nephrotic syndrome, ulcerative
colitis, regional ileitis (Crohn's
disease) pemphigus, sarcoidosis (especially with hypercalcaemia),
rheumatic carditis, ankylosing
spondylitis.
CONTRAINDICATIONS:
In patients with systemic infections unless specific anti-infective
therapy is employed. Live-virus
immunisation. In
patients who are sensitive to prednisolone and its salts.
SIDE EFFECTS:
Prolonged treatment with corticosteroids in high dosage is
occasionally associated with subcapsular
cataract, skin thinning, osteoporosis and glaucoma. In addition, any
of the features of
hypercorticism, such as suppression of the HPA axis, may occur.
Aseptic osteonecrosis,
particularly of the femoral head, may occur after prolonged
corticosteroid therapy, or after repeated
short cou