Locoid Crelo 0.1%

Negara: Malta

Bahasa: Inggris

Sumber: Medicines Authority

Bahan aktif:

hydrocortisone butyrate 1 mg/g

Tersedia dari:

Astellas Pharma Europe B.V.

Kode ATC:

D07AB02

INN (Nama Internasional):

hydrocortisone butyrate

Bentuk farmasi:

cutaneous emulsion

Status otorisasi:

Authorised

Tanggal Otorisasi:

2005-09-23

Selebaran informasi

1 

LOCOID CRELO
® 
0.1% topical emulsion  
Information for the user 
_______________________________________________________________________________________________ 
We advise you to read this package insert, also if you have
used Locoid Crelo before. 
The information may have changed. 

WHAT IS LOCOID CRELO AND HOW DOES IT 
WORK?  

_Composition _
Locoid Crelo topical emulsion contains as 
active ingredient 1 mg hydrocortisone 
17-butyrate per gram. The other 
ingredients are: cetomacrogol 1000, 
cetostearyl alcohol, white soft paraffin, 
hard paraffin, borage oil, butyl hydroxytoluene, 
propylene glycol, sodium citrate, 
citric acid, propyl hydroxybenzoate, butyl 
hydroxybenzoate and purified water. 
_ _
_What does Locoid Crelo look like and _
_how is it supplied ? _
Locoid Crelo topical emulsion is white and 
is packed in bottles of 30 g. The bottle is 
packed in a yellow/grey/white box 
imprinted Locoid Crelo 0,1%. 
_ _
_How does Locoid Crelo topical emulsion _
_work? _
Locoid Crelo contains an adrenal cortex 
hormone (corticosteroid) and decreases 
quickly the symptoms, such as itching, 
redness or scaling of the skin, which 
occur in certain skin disorders. 
Corticosteroids in general do not cure the 
underlying disease. 
_ _
_Authorization holder and manufacturer _
Locoid Crelo has been registered in the 
name of and is manufactured by 
Astellas Pharma Europe B.V.,  Leiden, 
The Netherlands. Locoid Crelo 0.1% 
topical emulsion is only available on 
prescription. 

WHAT CAN LOCOID CRELO BE USED FOR? 
Locoid Crelo topical emulsion may be 
used for the treatment of superficial skin 
diseases in which itching, redness or 
scaling are often present. Locoid Crelo is 
especially suitable for the treatment of 
hairy skin. 

WHAT YOU SHOULD KNOW BEFORE USING 
LOCOID CRELO 
_ _
_When should you not use Locoid Crelo? _
Loco

Karakteristik produk

Page 1 of 6 
SUMMARY OF PRODUCT CHARACTERISTICS 
1. NAME OF THE MEDICINAL PRODUCT 
Locoid
®
 ointment 0.1% 
Locoid Lipocream
®
, cream 0.1% 
Locoid
®
 cream 0.1% 
Locoid Crelo
®
, cutaneous emulsion 0.1% 
Locoid
®
 scalp lotion 0.1% 

2. QUALITATIVE AND QUANTITATIVE COMPOSITION 
Locoid ointment and cream, Locoid Lipocream and Locoid Crelo
contain 1 mg/g and Locoid lotion 
1mg/ml hydrocortisone 17-butyrate. 
The ointment base is hydrophobic (fat); Locoid cream, Locoid
Lipocream and Locoid Crelo contain 
buffered oil-in-water emulsions (Locoid Lipocream contains more fat,
Locoid cream and Locoid 
Crelo more water). The lotion is buffered, somewhat viscous and
based on isopropanol-water. 

3. PHARMACEUTICAL FORM 
Ointment, cream, cutaneous emulsion and cutaneous solution. 

4. CLINICAL PARTICULARS 
4.1 THERAPEUTIC INDICATIONS 
Superficial, corticosteroid responsive dermatoses, which are not
caused by micro-organisms.  
Follow-up or maintenance treatment of dermatoses which have
been suppressed previously by a 
stronger corticosteroid. 
4.2 POSOLOGY AND METHOD OF ADMINISTRATION 
Apply 1-3 times daily a small amount of Locoid to the skin.  
After improvement of the disorder, application once daily or two
to three times a week is usually 
adequate. 
Do not use more than 30-60 g per week in general. 
Locoid should be applied evenly in a thin layer onto the diseased
skin. 
To promote penetration it may be lightly massaged into the skin. 
Occlusion may be necessary to obtain a better therapeutic result. 

Page 2 of 6 
4.3 CONTRAINDICATIONS 
-  Skin lesions caused by: 
o
  bacterial infections (e.g. pyodermias, luetic
and tuberculous processes) 
o
  viral infections (e.g. varicellae, herpes simplex, herpes zoster,
verrucae vulgares, verrucae 
planae, condylomata, mollusca contagiosa) 
o
  mycotic and yeast infections 
o
  parasitic infections (e.g. scabies) 
-  Ulcerous skin lesions, wounds