Negara: Malaysia
Bahasa: Inggris
Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Glucosamine Sulfate KCl; Chondroitin Sulphate Sodium; METHYLSULFONYLMETHANE
PAHANG PHARMACY SDN. BHD.
Glucosamine Sulfate KCl; Chondroitin Sulphate Sodium; METHYLSULFONYLMETHANE
10sachet Sachets; 30sachet Sachets; 15 Sachets; 20 Sachets
Noripharma Sdn. Bhd.
LIVE-WELL TM OSTESAMIN TM _ PLUS _ CHONDROITIN & MSM POWDER Each 5.8g sachet contains: Glucosamine Sulphate Potassium Chloride equiv. to Glucosamine Sulphate 1500mg Chondroitin Sulphate Sodium 1200mg equiv. to Chondroitin Sulphate 1078mg MSM (Methylsulfonylmethane) 1000mg DESCRIPTION: Powder: A yellow powder with odour of orange flavour Solution: A yellow solution with odour of orange flavour. PHARMACODYNAMICS: Glucosamine plays a major role in the promotion and maintenance of the structure and function of cartilage in the bone joint. Glucosamine stimulates the biosynthesis of mucopolysaccharides which is the key structural components of joint cartilage which are essential for proper joint function. Glucosamine also increases synovial fluid production and viscosity, giving better lubricant activity for the joints. Glucosamine sulphate is well-absorbed after oral intake, and is distributed mainly to bones and joint tissues. Chondroitin sulfate is vital for the structure and function of articular cartilage. Chondroitin sulfate is an important component of aggrecan which is found in articular cartilage. Aggrecan confers upon articular cartilage shock-absorbing properties. It does this by providing cartilage with a swelling pressure that is restrained by the tensile force of collagen fibers. This balance confers upon articular cartilage the deformable resilience vital to its function. Methylsulfonylmethane (MSM) is an organic sulphur-containing compound. It is an oxidation product of the organic solvent, dimethyl sulfoxide (DMSO). DMSO has been used in the treatment of arthritis and connective tissue injuries because cartilage has a high content of sulphur, and sulphur is needed for the formation of connective tissue, MSM as a source of sulphur could be useful in the management of conditions such as osteoarthritis and joint injuries where there is degeneration or destruction of cartilage. PHARMACOKINETICS: Glucosamine: _ABSORPTION _ After oral administration, bioavailability is low due to first-pass hepatic metabolis Baca dokumen lengkapnya