Klacid

Negara: Australia

Bahasa: Inggris

Sumber: Department of Health (Therapeutic Goods Administration)

Bahan aktif:

Clarithromycin

Tersedia dari:

Abbott Australasia Pty Ltd

Kelas:

Medicine Registered

Selebaran informasi

KLACID
®

_Clarithromycin_
CONSUMER MEDICINE INFORMATION (CMI)

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about this medicine.
It does not contain all of the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have benefits and
risks. Your doctor has weighed the
risks of you taking Klacid against the
benefits they expect it will have on
you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, TALK TO YOUR
DOCTOR OR PHARMACIST.
Keep this leaflet with your medicine.
You may need to read it again.
WHAT KLACID IS USED
FOR
Klacid is used to treat certain
bacterial infections, including the
following:
•
respiratory tract infections
•
skin infections
•
peptic ulcer
Klacid is also used to prevent a
specific bacterial infection associated
with HIV infection.
Your doctor, however, may have
prescribed Klacid for another
purpose. Ask your doctor if you have
any questions about why Klacid has
been prescribed for you.
Klacid is an antibiotic that belongs to
the group of medicines called
macrolides. These medicines work
by killing or stopping the growth of
bacteria which cause infections.
Klacid will not work against
infections caused by viruses, such as
colds or flu.
Klacid is available only with a
doctor's prescription.
KLACID TO TREAT PEPTIC ULCER
Peptic ulcers are associated with an
infection in the intestine and stomach
by a bacteria called Helicobacter
pylori (H. pylori). Nearly all patients
with peptic ulcers are infected with
this bacteria.
The H. pylori infection can be treated
with a combination of Klacid
(clarithromycin), another antibiotic
(amoxycillin) and another medicine
called omeprazole (used to control
the acidity of the stomach).
However, the best combination of
tablets to treat H. pylori infection is
yet to be determined. Your doctor
will determine the best combination
for you.
If your symptoms return, consult
your doctor. It is possible that Klacid
may no longer be effective in killing
the H. pylori infection

Karakteristik produk

 
Klacid 250mg and 500mg Tablets 
Klacid 250mg/5mL Oral Liquid 
Version 14  
5 September 2013 
1 of 24 

PRODUCT INFORMATION 
KLACID
®

NAME OF THE MEDICINE 
Clarithromycin  
CHEMICAL STRUCTURE 
Chemically, it is 6-0-Methyl Erythromycin A. 
The  molecular  formula  is  C
38
H
69
NO
13
,  the  molecular  weight  is  747.96  and  the  structural 
formula is: 

DESCRIPTION 
Klacid (clarithromycin) is a semi-synthetic macrolide antibiotic. Clarithromycin is a white to off-
white  crystalline  powder.  It  is  soluble  in  acetone,  slightly  soluble  in  methanol,  ethanol  and 
acetonitrile and practically insoluble in water.  
The  250  mg  tablet  is  yellow,  oval  and  film-coated,  containing  250  mg  clarithromycin.  The 
500 mg tablet is pale yellow, oval and
film-coated, containing 500 mg clarithromycin.  
Klacid Powder for Oral Liquid consists of a granulation of clarithromycin and carbomer 934P 
and  coated  with  HP-55  polymer  (hypromellose  phthalate).  The  250  mg/5  mL  suspension  is 
fruit  punch  flavoured  and  sweetened  with  sucrose.  Water  is  added  to  reconstitute  the 
suspension prior to use. After mixing, each 5 mL contains
250 mg of clarithromycin. 
PHARMACOLOGY 
Hepatotoxicity, atrophy of lymphatic tissues (lymph, thymus) and adverse reproductive toxicity 
were seen in several species at exposures less than those which might be expected clinically 
at proposed doses. The clinical significance of these observations is not known. There are no 
data from long-term animal carcinogenicity studies. 
CLINICAL PHARMACOLOGY 
_Helicobacter  pylori_  is  strongly  associated  with  peptic  ulcer  disease.  90  to  100%  of  patients 
with peptic ulcers are infected with this pathogen. Eradicat