Negara: Australia
Bahasa: Inggris
Sumber: Department of Health (Therapeutic Goods Administration)
Perindopril erbumine; Indapamide hemihydrate
Servier Laboratories (Australia) Pty Ltd
Medicine Registered
IDAPREX ® COMBI 4/1.25 1 IDAPREX ® COMBI 4/1.25 _perindopril (pronounced per-in-do-pril) and indapamide (pronounced in-dap-a-mide) _ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about IDAPREX COMBI 4/1.25. It does not contain all the available information about this medicine. Reading this leaflet does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking IDAPREX COMBI 4/1.25 against the expected benefits for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT IDAPREX COMBI 4/1.25 IS The name of your medicine is IDAPREX COMBI 4/1.25. The medicine contains the active ingredients perindopril erbumine and indapamide hemihydrate. Perindopril belongs to a group of medicines called angiotensin converting enzyme (ACE) inhibitors. Indapamide belongs to a group of medicines called chlorosulphamoyl diuretics. WHAT IDAPREX COMBI 4/1.25 IS USED FOR YOU HAVE BEEN PRESCRIBED IDAPREX COMBI 4/1.25 FOR HIGH BLOOD PRESSURE. IDAPREX COMBI 4/1.25 is available only with a doctor's prescription. There is no evidence that IDAPREX COMBI 4/1.25 is addictive. _WHY IDAPREX COMBI 4/1.25 _ _IS USED FOR HIGH BLOOD _ _PRESSURE _ Everyone has blood pressure. This pressure helps to circulate blood all around the body. Your blood pressure may be different at different times of the day, depending on how busy or stressed you are. You have high blood pressure (also known as hypertension) when your blood pressure stays higher than is needed, even when you are calm and relaxed. If high b Baca dokumen lengkapnya
IDAPREX COMBI 4/1.25 – PRODUCT INFORMATION 1 (26) Version 4a PRODUCT INFORMATION NAME OF THE MEDICINE _IDAPREX COMBI 4/1.25 _ Perindopril erbumine 4 mg / Indapamide hemihydrate 1.25 mg Perindopril erbumine Perindopril erbumine is a dipeptide monoacid monoester with a perhydroindole group and no sulphydryl radical; chemical name, tert-butylammonium (2_S_, 3a_S_, 7a_S_)-1-(_N_-[(_S_)-1-ethoxycarbonyl butyl]-L-alanyl) perhydroindole-2-carboxylate. _CAS Registry Number _: 107133-36-8 _ _ _Molecular formula _: C 19 H 32 N 2 O 5 , C 4 H 11 N _Chemical structure _: Indapamide Indapamide is a non thiazide indole derivative of chlorosulphonamide; chemical name 4-chloro-_N_- (2 methyl-1-indolinyl)-3-sulphamoyl benzamide hemihydrate. _CAS Registry Number _: 26807-65-8 _Molecular formula _: C 16 H 16 ClN 3 O 3 S, ½ H2O _Chemical structure _: DESCRIPTION Active Ingredients Perindopril erbumine is a white powder, readily soluble in purified water, ethanol and chloroform. Perindopril has five asymmetric centres and is synthesised stereoselectively so that it is a single enantiomer (all _S_ stereochemistry). , ½ H 2 O IDAPREX COMBI 4/1.25 – PRODUCT INFORMATION 2 (26) Version 4a Indapamide is a white crystalline lipophilic powder, soluble in methanol, ethanol, acetic acid and ethyl acetate, very slightly soluble in ether, chloroform and benzene and practically insoluble in water. Excipients Microcrystalline cellulose, lactose, magnesium stearate, colloidal anhydrous silica._ _ PHARMACOLOGY MECHANISM OF ACTION IDAPREX COMBI 4/1.25 is a combination of perindopril erbumine, an angiotensin converting enzyme (ACE) inhibitor, and indapamide, a chlorosulphamoyl diuretic, in which the dose Baca dokumen lengkapnya