GENTAVETO-5 VETERINARY

Negara: Israel

Bahasa: Inggris

Sumber: Ministry of Health

Bahan aktif:

GENTAMICIN AS SULFATE

Tersedia dari:

UDIM, ISRAEL

Bentuk farmasi:

SOLUTION FOR INJECTION

Komposisi:

GENTAMICIN AS SULFATE 50 MG/ML

Rute administrasi :

S.C, I.M

Jenis Resep:

Required

Diproduksi oleh:

V.M.D. N.V., BELGIUM

Indikasi Terapi:

Infections caused by micro-organisms susceptible to gentamycin, as occuring in urogenital, respiratory tissues, skin, uterus and gastrointestinal infections in horses, dogs and cats and pigs.

Tanggal Otorisasi:

2010-08-31

Karakteristik produk

GENTAVETO-5 PRO INJ
COMPOSITION:
per ml solution: 50 mg gentamicin base (as sulfate).
Spectrum:
Gentamicin is an antibiotic belonging to the group of aminiglycosides.
It has bactericidal activity
against Gram-positive bacteria (including: Pseudomonas spp.,
Enterobacter spp., E.Coli, Proteus spp.,
Salmonella spp., Staphylococci,…). Gentamicin may be active against
bacteria which are resistant to
other aminoglycoside antibiotics (such as streptomycin and kanamycin).
After intramuscular administration, maximum serum concentrations are
obtained within 30-60 minutes.
Gentamicin is mainly excreted by the kidneys, resulting in high
concentrations of the active compound
in the urine.
INDICATIONS:
Infections caused by micro-organisms susceptible to gentamicin, as
occurring in urogenital, respiratory,
tissue, skin, uterus and gastrointestinal infections in horses, dogs,
cats and pigs.
CONTRAINDICATIONS:
Hypersensitivity to aminoglycoside antibiotics, renal dysfunctions,
vestibular, ear or visual
dysfunctions, combinations with potential nephrotoxic or
muscle-paralysing medicines.
PRECAUTIONS:
The only half of the normal dose must be given to animals with
impaired renal functions.
The following conditions have been found to contribute to the toxicity
of gentamicin in dogs:
-
Prior renal damage (most commonly found in dogs of advanced age) and
dogs infected with
heartworm microfilaria.
-
Hypovolemic dehydration (dehydrated patients should be rehydrated
prior to initiating
therapy). In dogs where decreased renal function is suspected prior to
treatment, BUN or
serum creatinine levels may not indicate the degree of kidney
impairment. A creatinine
clearance determination may be more useful. Monitoring of renal
function during treatment is
recommended. Although there is not a completely reliable monitoring
program for gentamicin
toxicity, urinalysis which may indicate toxicity include:
-
Decreased specific gravity in the absence of fluid therapy.
-
Appearance in the urine of casts, albumin, glucose or blood in the
absence of p