FLOREXA- eflornithine hydrochloride cream

Negara: Amerika Serikat

Bahasa: Inggris

Sumber: NLM (National Library of Medicine)

Bahan aktif:

EFLORNITHINE HYDROCHLORIDE (UNII: 4NH22NDW9H) (EFLORNITHINE - UNII:ZQN1G5V6SR)

Tersedia dari:

Pella Pharmaceuticals Co. Ltd

Rute administrasi :

TOPICAL

Jenis Resep:

PRESCRIPTION DRUG

Indikasi Terapi:

Florexa is indicated for the reduction of unwanted facial hair in women. Florexa has only been studied on the face and adjacent involved areas under the chin of affected individuals. Usage should be limited to these areas of involvement. Eflomithine HCl is contraindicated in patients with a history of sensitivity to any components of the preparation. Children less than 12 years of age shouldn't use Florexa .

Ringkasan produk:

30 g packs

Status otorisasi:

unapproved drug other

Karakteristik produk

FLOREXA- EFLORNITHINE HYDROCHLORIDE CREAM
PELLA PHARMACEUTICALS CO. LTD
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this_
_labeling has not been approved by FDA. For further information about
unapproved_
_drugs, click here._
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FLOREXA
COMPOSITION
Each 1 g contains: Eflornithine hydrochloride 139 mg.
Excipients: Ceteareth-25, Cetostearyl alcohol, Lanolin, Glyceryl
monostearate, mineral oil,
Cetyl alcohol, Methyl Paraben, Emulsifying wax, Dimethicone, and
Purified Water.
PROPERTIES
FLOREXA is a prescribed medication applied to the skin for the
reduction of unwanted
facial hair in women.
There are no studies examining the inhibition of the enzyme ornithine
decarboxylase
(ODC) in human skin following the application of topical eflornithine.
However, there are
studies in the literature that report the inhibition of ODC activity
in skin following oral
eflornithine. It is postulated that topical eflornithine hydrochloride
irreversibly inhibits skin
ODC activity. This enzyme is necessary in the synthesis of polyamines.
Animal data
indicate that inhibition of ornithine decarboxylase inhibits cell
division and synthetic
functions, which affect the rate of hair growth. Eflornithine
hydrochloride Cream 13.9%
has been shown to retard the rate of hair growth in non-clinical and
clinical studies.
INDICATIONS
FLOREXA is indicated for the reduction of unwanted facial hair in
women. FLOREXA has
only been studied on the face and adjacent involved areas under the
chin of affected
individuals. Usage should be limited to these areas of involvement.
CONTRAINDICATIONS
Eflomithine HCl is contraindicated in patients with a history of
sensitivity to any
components of the preparation.
Children less than 12 years of age shouldn't use FLOREXA.
PRECAUTIONS
FOR EXTERNAL USE ONLY.
Transient stinging or burning may occur when applied to abraded or
broken skin.
PREGNANCY
Because there are no adequate and well-controlled studies in pregnant
women, the risk /
benefit ratio of using eflornithine HCl in wome